Mark Sabat, Ph.D.

Affiliations: 
2001 Wayne State University, Detroit, MI, United States 
Area:
organosulfur chemistry, synthetic methods
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"Mark Sabat"
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Carl Randolph Johnson grad student 2001 Wayne State
 (Synthesis of novel unnatural amino acids.)
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Publications

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Ruan Z, Haley E, Orozco IJ, et al. (2021) Author Correction: Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nature Structural & Molecular Biology
Ruan Z, Haley E, Orozco IJ, et al. (2021) Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nature Structural & Molecular Biology
Barilli A, Aldegheri L, Bianchi F, et al. (2021) From High-Throughput Screening to Target Validation: Benzo[]isothiazoles as Potent and Selective Agonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 5 Possessing In Vivo Gastrointestinal Prokinetic Activity in Rodents. Journal of Medicinal Chemistry
Bigi-Botterill SV, Ivetac A, Bradshaw EL, et al. (2020) Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp character and an exquisite selectivity profile. Bioorganic & Medicinal Chemistry Letters. 30: 127405
Lanier M, Pickens J, Bigi SV, et al. (2017) Correction to "Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure". Acs Medicinal Chemistry Letters. 8: 1341
Cheruvallath ZS, Gwaltney SL, Sabat M, et al. (2017) Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators. Bioorganic & Medicinal Chemistry Letters
Sabat M, Wang H, Scorah N, et al. (2017) Design, synthesis and optimization of 7-substituted-pyrazolo[4,3-b]pyridine ALK5 (activin receptor-like kinase 5) inhibitors. Bioorganic & Medicinal Chemistry Letters
Lanier M, Pickens J, Bigi SV, et al. (2017) Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure. Acs Medicinal Chemistry Letters. 8: 316-320
Wang H, Lawson JD, Scorah N, et al. (2016) Design, synthesis and optimization of novel Alk5 (activin-like kinase 5) inhibitors. Bioorganic & Medicinal Chemistry Letters
MacLeod BL, Pienkos JA, Wilson KB, et al. (2016) Synthesis of Novel Hexahydroindoles from the Dearomatization of Indoline Organometallics. 35: 370-387
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