Hilda A. Namanja, Ph.D.
Affiliations: | 2012 | Chemistry | Purdue University, West Lafayette, IN, United States |
Area:
Chemical BiologyGoogle:
"Hilda Namanja"Mean distance: 7.74 | S | N | B | C | P |
Parents
Sign in to add mentor| Jean Anne Chmielewski | grad student | 2012 | Purdue | |
| (Development of dimeric prodrug inhibitors of P-glycoprotein and ABCG2 to enhance brain penetration of antiretroviral agents.) | ||||
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Publications
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| Emmert D, Campos CR, Ward D, et al. (2014) Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier. Acs Chemical Neuroscience. 5: 305-17 |
| Hrycyna CA, Summers RL, Lehane AM, et al. (2014) Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparum. Acs Chemical Biology. 9: 722-30 |
| Namanja HA, Emmert D, Hrycyna CA, et al. (2013) Homodimers of the Antiviral Abacavir as Modulators of P-glycoprotein Transport in Cell Culture: Probing Tether Length. Medchemcomm. 4 |
| Namanja HA, Emmert D, Davis DA, et al. (2012) Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers. Journal of the American Chemical Society. 134: 2976-80 |
| Namanja HA, Emmert D, Pires MM, et al. (2009) Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer. Biochemical and Biophysical Research Communications. 388: 672-6 |