Matthew M. Bio, Ph.D.

Affiliations: 
2001 Columbia University, New York, NY 
Area:
Organic synthesis
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"Matthew Bio"
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SNBCP

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James L. Leighton grad student 2001 Columbia
 (Studies toward a total synthesis of CP -263,114.)
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Publications

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Monfette S, Fang Y, Bio MM, et al. (2020) Continuous Process for Preparing the Difluoromethylating Reagent [(DMPU)2Zn(CF2H)2] and Improved Synthesis of the ICHF2 Precursor Organic Process Research & Development. 24: 1077-1083
Breen CP, Parrish C, Shangguan N, et al. (2020) A Scalable Membrane Pervaporation Approach for Continuous Flow Olefin Metathesis Organic Process Research & Development. 24: 2298-2303
Li H, Breen CP, Seo H, et al. (2018) Ni-Catalyzed Electrochemical Decarboxylative C-C Couplings in Batch and Continuous Flow. Organic Letters
Li H, Sheeran JW, Clausen AM, et al. (2017) Flow Asymmetric Propargylation: Development of Continuous Processes for the Preparation of a Chiral β-Amino Alcohol. Angewandte Chemie (International Ed. in English)
Fang Y, Li H, Sheeran JW, et al. (2017) Flow Asymmetric Propargylation: Development of Continuous Processes for a Chiral beta-Amino Alcohol Angewandte Chemie
Beaver MG, Langille NF, Cui S, et al. (2016) Crystallization-Induced Dynamic Resolution of a Diarylmethylamine toward the Synthesis of a Potent TRPM8 Inhibitor Organic Process Research & Development. 20: 1341-1346
Chen Y, Huang J, Hwang TL, et al. (2015) Highly Regioselective Halogenation of Pyridine N-Oxide: Practical Access to 2-Halo-Substituted Pyridines. Organic Letters. 17: 2948-51
Mennen SM, Mak-Jurkauskas ML, Bio MM, et al. (2015) Synthesis of 4-Substituted Phthalazin-1(2H)-ones from 2-Acylbenzoic Acids: Controlling Hydrazine in a Pharmaceutical Intermediate through PAT-Guided Process Development Organic Process Research and Development. 19: 884-891
Huckins JR, Bercot EA, Thiel OR, et al. (2013) Rh(III)-catalyzed C-H activation and double directing group strategy for the regioselective synthesis of naphthyridinones. Journal of the American Chemical Society. 135: 14492-5
Cleator E, Scott JP, Avalle P, et al. (2013) Process Development and Multikilogram-Scale Synthesis of a TRPV1 Antagonist Organic Process Research and Development. 17: 1561-1567
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