Hui Huang, Ph.D.

Affiliations: 
2000 Northwestern University, Evanston, IL 
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology
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"Hui Huang"
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Richard B. Silverman grad student 2000 Northwestern
 (N(omega)-nitroarginine-containing dipeptides: Potent and selective inhibitors of neuronal nitric oxide synthase.)
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Publications

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Chen J, Wen K, Chen H, et al. (2020) Achieving High-Performance Photothermal and Photodynamic Effects upon Combining D-A Structure and Nonplanar Conformation. Small (Weinheim An Der Bergstrasse, Germany). e2000909
Ye P, Chen Y, Wu J, et al. (2019) Combination of noncovalent conformational locks and side chain engineering to tune the crystallinity of nonfullerene acceptors for high-performance P3HT based organic solar cells Materials Chemistry Frontiers. 3: 64-69
Dong T, Lv L, Feng L, et al. (2017) Noncovalent Se···O Conformational Locks for Constructing High-Performing Optoelectronic Conjugated Polymers. Advanced Materials (Deerfield Beach, Fla.)
Yu S, Chen Y, Yang L, et al. (2017) Significant enhancement of photovoltaic performance through introducing S⋯N conformational locks Journal of Materials Chemistry. 5: 21674-21678
Igarashi J, Li H, Flinspach III ML, et al. (2006) 1P157 Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases(5. Heme protein,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) Seibutsu Butsuri. 46: S186
Li H, Flinspach ML, Igarashi J, et al. (2005) Exploring the binding conformations of bulkier dipeptide amide inhibitors in constitutive nitric oxide synthases. Biochemistry. 44: 15222-9
Flinspach M, Li H, Jamal J, et al. (2004) Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound. Biochemistry. 43: 5181-7
Flinspach ML, Li H, Jamal J, et al. (2004) Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nature Structural & Molecular Biology. 11: 54-9
Huang H, Martásek P, Roman LJ, et al. (2001) Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase. Journal of Enzyme Inhibition. 16: 233-9
Huang H, Hah JM, Silverman RB. (2001) Mechanism of nitric oxide synthase. Evidence that direct hydrogen atom abstraction from the O-H bond of NG-hydroxyarginine is not relevant to the mechanism. Journal of the American Chemical Society. 123: 2674-6
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