Jiwon Seo, Ph.D.

Affiliations: 
2006 Northwestern University, Evanston, IL 
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology
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"Jiwon Seo"
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Richard B. Silverman grad student 2006 Northwestern
 (NG-nitro-L-arginine-containing peptidomimetics as selective neuronal nitric oxide synthase inhibitors. Structure-based design, synthesis, and biological evaluation and approaches toward enhanced CNS activity.)
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Publications

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Goh B, Choi J, Kang JA, et al. (2019) Development of a mass spectrometric screening assay for hepatitis B virus entry inhibitors. Journal of Pharmaceutical and Biomedical Analysis. 112959
Kang S, Lee S, Yang W, et al. (2016) A direct assay of butyrylcholinesterase activity using a fluorescent substrate. Organic & Biomolecular Chemistry. 14: 8815-8820
Shin MW, Bae SJ, Wee HJ, et al. (2015) Ninjurin1 regulates lipopolysaccharide-induced inflammation through direct binding. International Journal of Oncology
Huang W, Seo J, Willingham SB, et al. (2014) Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity. Plos One. 9: e90397
Silverman RB, Lawton GR, Ranaivo HR, et al. (2009) Effect of potential amine prodrugs of selective neuronal nitric oxide synthase inhibitors on blood-brain barrier penetration Bioorganic and Medicinal Chemistry. 17: 7593-7603
Seo J, Igarashi J, Li H, et al. (2007) Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water. Journal of Medicinal Chemistry. 50: 2089-99
Seo J, Martásek P, Roman LJ, et al. (2007) Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors. Bioorganic & Medicinal Chemistry. 15: 1928-38
Mbadugha BN, Seo J, Ji H, et al. (2006) Hydroxyl-terminated peptidomimetic inhibitors of neuronal nitric oxide synthase. Bioorganic & Medicinal Chemistry. 14: 3681-90
Seo J, Silverman RB. (2006) Synthesis of arginine-containing hydroxamate dipeptidomimetics Tetrahedron Letters. 47: 4069-4073
Erdal EP, Litzinger EA, Seo J, et al. (2005) Selective neuronal nitric oxide synthase inhibitors. Current Topics in Medicinal Chemistry. 5: 603-24
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