Lada Klaic, Ph.D.

Affiliations: 
2010 Chemistry Northwestern University, Evanston, IL 
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology
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"Lada Klaic"
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Parents

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Richard B. Silverman grad student 2010 Northwestern
 (Celastrol - Chemical and Biological Studies Toward Elucidating the Intracellular Mechanism of Action.)
William Clemons post-doc 2011-2016 Caltech
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Publications

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Klaić L, Morimoto RI, Silverman RB. (2012) Celastrol analogues as inducers of the heat shock response. Design and synthesis of affinity probes for the identification of protein targets. Acs Chemical Biology. 7: 928-37
Klaić L, Trippier PC, Mishra RK, et al. (2011) Remarkable stereospecific conjugate additions to the Hsp90 inhibitor celastrol. Journal of the American Chemical Society. 133: 19634-7
Trott A, West JD, Klai? L, et al. (2008) Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. Molecular Biology of the Cell. 19: 1104-12
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