Paul M. Wehn, Ph.D.
Affiliations: | 2006 | Stanford University, Palo Alto, CA |
Area:
Organic, Inorganic and Biological ChemistryGoogle:
"Paul Wehn"Mean distance: 8.23 | S | N | B | C | P |
Parents
Sign in to add mentor| Justin Du Bois | grad student | 2006 | Stanford | |
| (The development and application of rhodium-catalyzed carbon-hydrogen amination reactions in the synthesis of bromopyrrole alkaloids: Enantioselective synthesis of (-)-manzacidin A, (+)-manzacidin C, and (-)-agelastatin A.) | ||||
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| Wehn PM, Rizzi JP, Dixon DD, et al. (2018) Design and Activity of Specific Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385). Journal of Medicinal Chemistry |
| Wehn PM, Harrington PE, Eksterowicz JE. (2009) Facile synthesis of substituted 5-amino- and 3-amino-1,2,4-thiadiazoles from a common precursor. Organic Letters. 11: 5666-9 |
| Wehn PM, Du Bois J. (2009) A stereoselective synthesis of the bromopyrrole natural product (-)-agelastatin A. Angewandte Chemie (International Ed. in English). 48: 3802-5 |
| Guthikonda K, Wehn PM, Caliando BJ, et al. (2006) Rh-catalyzed alkene oxidation: a highly efficient and selective process for preparing N-alkoxysulfonyl aziridines Tetrahedron. 62: 11331-11342 |
| Wehn PM, Du Bois J. (2005) Exploring new uses for C-H amination: Ni-catalyzed cross-coupling of cyclic sulfamates Organic Letters. 7: 4685-4688 |
| Wehn PM, Lee J, Du Bois J. (2003) Stereochemical Models for Rh-Catalyzed Amination Reactions of Chiral Sulfamates Organic Letters. 5: 4823-4826 |
| Wehn PM, Du Bois J. (2002) Enantioselective synthesis of the bromopyrrole alkaloids manzacidin A and C by stereospecific C-H bond oxidation Journal of the American Chemical Society. 124: 12950-12951 |
| Espino CG, Wehn PM, Chow J, et al. (2001) Synthesis of 1,3-difunctionalized amine derivatives through selective C-H bond oxidation Journal of the American Chemical Society. 123: 6935-6936 |
| Moreira RF, Wehn PM, Sames D. (2000) Highly Regioselective Oxygenation of C-H Bonds: Diamidomanganese Constructs with Attached Substrates as Catalyst Models Financial support has been provided by Columbia University and the Camille and Henry Dreyfus Foundation. P.M.W. acknowledges the REU-NSF program for summer support. We also thank Dr. J. B. Schwarz (manuscript preparation) and Dr. Y. Itagaki (mass spectrometry). Angewandte Chemie (International Ed. in English). 39: 1618-1621 |