Shilpa A. Worlikar, Ph.D.

Affiliations: 
2008 Chemistry Iowa State University, Ames, IA, United States 
Area:
palladium catalysts in organic synthesis
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"Shilpa Worlikar"
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Richard Craig Larock grad student 2008 Iowa State
 (Palladium-catalyzed and electrophilic cyclization approaches to carbocycles and heterocycles.)
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Publications

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He S, Jain P, Lin B, et al. (2015) High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors. Acs Combinatorial Science
Jung KY, Samadani R, Chauhan J, et al. (2013) Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signaling. Organic & Biomolecular Chemistry. 11: 3706-32
Yap JL, Worlikar S, MacKerell AD, et al. (2011) Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeutics. Chemmedchem. 6: 38-48
Worlikar SA, Larock RC. (2011) Pd-catalyzed reactions involving arynes Current Organic Chemistry. 15: 3214-3232
Durán-Galván M, Worlikar SA, Connell BT. (2010) Enantioselective synthesis of butadien-2-ylcarbinols via (silylmethyl)allenic alcohols from chromium-catalyzed additions to aldehydes utilizing chiral carbazole ligands Tetrahedron. 66: 7707-7719
Worlikar SA, Larock RC. (2009) Synthesis of 9-fluorenylidenes and 9,10-phenanthrenes through palladium-catalyzed aryne annulation by o-halostyrenes and o-halo allylic benzenes Journal of Organic Chemistry. 74: 9132-9139
Worlikar SA, Neuenswander B, Lushington GH, et al. (2009) Highly substituted indole library synthesis by palladium-catalyzed coupling reactions in solution and on a solid support Journal of Combinatorial Chemistry. 11: 875-879
Worlikar SA, Larock RC. (2009) Palladium-catalyzed synthesis of 9-fluorenylidenes through aryne annulation. Organic Letters. 11: 2413-6
Worlikar SA, Larock RC. (2008) Palladium-catalyzed one-step synthesis of isoindole-1,3-diones by carbonylative cyclization of o-halobenzoates and primary amines. The Journal of Organic Chemistry. 73: 7175-80
Worlikar SA, Kesharwani T, Yao T, et al. (2007) Synthesis of 3,4-disubstituted 2H-benzopyrans through C-C bond formation via electrophilic cyclization. The Journal of Organic Chemistry. 72: 1347-53
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