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Philip A. Beachy

Affiliations: 
Biochemistry Stanford University, Palo Alto, CA 
Area:
Hedgehog proteins and other extracellular signals in morphogenesis
Website:
http://med.stanford.edu/profiles/Philip_Beachy/
Google:
"Philip A. Beachy"
Bio:

http://www.nasonline.org/member-directory/members/20002141.html
http://stemcell.stanford.edu/about/Laboratories/beachy/index.html
http://dx.doi.org/10.1073/pnas.0408740102
http://cancer.stanford.edu/features/faculty/beachy.html
http://searchworks.stanford.edu/view/1216459

Mean distance: 5.63 (cluster 18)
 
SNBCP
Cross-listing: FlyTree

Parents

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David S. Hogness grad student 1986 Stanford
 (The Ubx domain in the bithorax complex of Drosophila)

Children

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Chien-Huan Chen grad student 2000 Johns Hopkins (FlyTree)
Yong Ma grad student 2003 Johns Hopkins (FlyTree)
Shenqin Yao grad student 2006 Johns Hopkins (FlyTree)
Sekyung Oh grad student 2008 Johns Hopkins (FlyTree)
Adrian Creanga grad student 2010 Johns Hopkins (FlyTree)
Michelle Monje post-doc (Neurotree)
Wan-Jin Lu post-doc 2011- Stanford (Stem Cell Tree)
James K. Chen post-doc 1999-2003 Johns Hopkins
Lay Teng Ang research scientist 2018- Stanford School of Medicine (Neurotree)
BETA: Related publications

Publications

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Jones RC, Karkanias J, Krasnow MA, et al. (2022) The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science (New York, N.Y.). 376: eabl4896
Wang Q, Asarnow DE, Ding K, et al. (2021) Dispatched uses Na flux to power release of lipid-modified Hedgehog. Nature
Zhang Y, Lu WJ, Bulkley DP, et al. (2020) Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit. Proceedings of the National Academy of Sciences of the United States of America
Deshpande I, Liang J, Hedeen D, et al. (2019) Smoothened stimulation by membrane sterols drives Hedgehog pathway activity. Nature
Zhang Y, Bulkley DP, Xin Y, et al. (2018) Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched. Cell
Raleigh DR, Sever N, Choksi PK, et al. (2018) Cilia-Associated Oxysterols Activate Smoothened. Molecular Cell. 72: 316-327.e5
Beachy P, Cai S, Ma Y, et al. (2018) Abstract P5-03-11: Targeted disruption of transcriptional effector GLI2 attenuates breast tumor growth and metastasis Cancer Research. 78
Kiss B, Kershner A, Lu W, et al. (2018) MP81-10 MOLECULAR CHARACTERIZATION OF THE MURINE URINARY BLADDER USING SINGLE CELL RNA SEQUENCING Journal of Urology. 199
Lu WJ, Mann RK, Nguyen A, et al. (2017) Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration. Proceedings of the National Academy of Sciences of the United States of America
Myers BR, Neahring L, Zhang Y, et al. (2017) Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium. Proceedings of the National Academy of Sciences of the United States of America
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