Jongsik Gam, Ph.D.

Affiliations: 
2004 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Antibody and Enzyme Engineering
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Brent L. Iverson grad student 2004 UT Austin
 (Toward high throughput directed evolution of protease specificity using fluorescence activated cell sorting.)
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Publications

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Lee J, Lee HJ, Lee Y, et al. (2022) Development of PD3 and PD3-B for PDEδ inhibition to modulate KRAS activity. Journal of Enzyme Inhibition and Medicinal Chemistry. 37: 1656-1666
Lim B, Park S, Park JH, et al. (2018) A metal-free and mild approach to 1,3,4-oxadiazol-2(3H)-ones via oxidative C-C bond cleavage using molecular oxygen. Organic & Biomolecular Chemistry
Lee R, Gam J, Moon J, et al. (2015) A critical element of the light-induced quaternary structural changes in YtvA-LOV. Protein Science : a Publication of the Protein Society
Gam J, Ha JS, Kim H, et al. (2015) Ratiometric analyses at critical temperatures can magnify the signal intensity of FRET-based sugar sensors with periplasmic binding proteins. Biosensors & Bioelectronics. 72: 37-43
Moon J, Gam J, Lee SG, et al. (2014) Light-regulated tetracycline binding to the Tet repressor. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 2508-14
Bhabha G, Lee J, Ekiert DC, et al. (2011) A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science (New York, N.Y.). 332: 234-8
Lee J, Yennawar NH, Gam J, et al. (2010) Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae. Biochemistry. 49: 195-206
Varadarajan N, Gam J, Olsen MJ, et al. (2005) Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity. Proceedings of the National Academy of Sciences of the United States of America. 102: 6855-60
Ki JJ, Kawarasaki Y, Gam J, et al. (2004) A periplasmic fluorescent reporter protein and its application in high-throughput membrane protein topology analysis. Journal of Molecular Biology. 341: 901-9
Jeong KJ, Kawarasaki Y, Gam JS, et al. (2004) Development of new periplasmic fluorescent reporter protein and its application in high-throughput membrane protein topology analysis Aiche Annual Meeting, Conference Proceedings. 8597
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