Hikari A. I. Yoshihara, Ph.D.
Affiliations: | 1995-2003 | University of California, San Francisco, San Francisco, CA | |
| 2003-2005 | Sunesis Pharmaceuticals, Inc. | ||
| 2005-2011 | University of California, San Francisco, San Francisco, CA | ||
| 2012-2015 | Lausanne University Hospital | ||
| 2015-2022 | Swiss Federal Institute of Technology (EPFL) | ||
| 2022- | University of Zurich / ETH Zurich |
Area:
metabolic applications of hyperpolarized carbon-13Google:
"Hikari Yoshihara"Mean distance: 8.67 | S | N | B | C | P |
Parents
Sign in to add mentor| Thomas S. Scanlan | grad student | 1997-2003 | UCSF | |
| (Studies of antagonists and selective agonists of the thyroid hormone receptors.) | ||||
| James A. Wells | post-doc | 2005-2009 | ||
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Publications
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| Crawford ED, Seaman JE, Agard N, et al. (2013) The DegraBase: a database of proteolysis in healthy and apoptotic human cells. Molecular & Cellular Proteomics : McP. 12: 813-24 |
| Yoshihara HA, Mahrus S, Wells JA. (2008) Tags for labeling protein N-termini with subtiligase for proteomics. Bioorganic & Medicinal Chemistry Letters. 18: 6000-3 |
| Yoshihara HA, Apriletti JW, Baxter JD, et al. (2003) Structural determinants of selective thyromimetics. Journal of Medicinal Chemistry. 46: 3152-61 |
| Webb P, Nguyen NH, Chiellini G, et al. (2002) Design of thyroid hormone receptor antagonists from first principles. The Journal of Steroid Biochemistry and Molecular Biology. 83: 59-73 |
| Scanlan TS, Yoshihara HA, Nguyen NH, et al. (2001) Selective thyromimetics: tissue-selective thyroid hormone analogs. Current Opinion in Drug Discovery & Development. 4: 614-22 |
| Yoshihara HA, Apriletti JW, Baxter JD, et al. (2001) A designed antagonist of the thyroid hormone receptor. Bioorganic & Medicinal Chemistry Letters. 11: 2821-5 |
| Chiellini G, Nguyen NH, Yoshihara HA, et al. (2000) Improved synthesis of the iodine-free thyromimetic GC-1. Bioorganic & Medicinal Chemistry Letters. 10: 2607-11 |
| Yoshihara HA, Chiellini G, Mitchison TJ, et al. (1998) An efficient substitution reaction for the preparation of thyroid hormone analogues. Bioorganic & Medicinal Chemistry. 6: 1179-83 |
| Chiellini G, Apriletti JW, Yoshihara HA, et al. (1998) A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chemistry & Biology. 5: 299-306 |