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Sujata Bardhan, Ph.D.

Affiliations: 
2007 Boston University, Boston, MA, United States 
Area:
synthesis of complex natural products
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"Sujata Bardhan"
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John A. Porco grad student 2007 Boston University
 (Studies toward the synthesis of epoxyquinoids and spiroisoxazoline natural products and derivatives.)

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Publications

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Porco JA, Su S, Lei X, et al. (2006) Total synthesis and structure assignment of (+)-hexacyclinol. Angewandte Chemie (International Ed. in English). 45: 5790-2
Bardhan S, Schmitt DC, Porco JA. (2006) Total synthesis and stereochemical assignment of the spiroisoxazoline natural product (+)-calafianin. Organic Letters. 8: 927-30
Liang MC, Bardhan S, Pace EA, et al. (2006) Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. Biochemical Pharmacology. 71: 634-45
Liang MC, Bardhan S, Porco JA, et al. (2006) The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkappaBalpha-deficient diffuse large B-cell lymphoma cell line. Cancer Letters. 241: 69-78
Liang MC, Bardhan S, Li C, et al. (2003) Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, blocks activation of transcription factor nuclear factor kappaB by inhibiting the inhibitor of kappaB kinase. Molecular Pharmacology. 64: 123-31
Li C, Bardhan S, Pace EA, et al. (2002) Angiogenesis inhibitor epoxyquinol a: total synthesis and inhibition of transcription factor NF-kappaB. Organic Letters. 4: 3267-70
Li C, Bardhan S, Pace EA, et al. (2002) Angiogenesis inhibitor epoxyquinol A: Total synthesis and inhibition of transcription factor NF-κB Organic Letters. 4: 3267-3270
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