David L. Sloman, Ph.D.

Affiliations: 
2011 Boston University, Boston, MA, United States 
Area:
synthesis of complex natural products
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John A. Porco grad student 2011 Boston University
 (Total synthesis of kibdelone C; Discovery of a novel platinum (IV) arylation.)
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Li D, Sloman DL, Achab A, et al. (2022) Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing. Journal of Medicinal Chemistry
Yu W, Deng Y, Sloman D, et al. (2021) Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold. Bioorganic & Medicinal Chemistry Letters. 128314
Wang Y, Cui L, Georgiev P, et al. (2021) Combination of EP antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells. Oncoimmunology. 10: 1896643
Quiroz RV, Reutershan MH, Schneider SE, et al. (2021) The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry
Mitcheltree MJ, Li D, Achab A, et al. (2020) Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Medicinal Chemistry Letters. 11: 582-588
Winter DK, Sloman DL, Porco JA. (2013) Polycyclic xanthone natural products: structure, biological activity and chemical synthesis. Natural Product Reports. 30: 382-91
Sloman DL, Bacon JW, Porco JA. (2011) Total synthesis and absolute stereochemical assignment of kibdelone C. Journal of the American Chemical Society. 133: 9952-5
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