Christopher M. Rath, Ph.D.

Affiliations: 
2011 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
cryptophycin anticancer drugs
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Parents

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David H. Sherman grad student 2011 University of Michigan
 (Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Analysis of Natural Product Biosynthesis.)
Kristina I. Hakansson grad student 2006-2011 University of Michigan
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Publications

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Skepper CK, Moreau RJ, Appleton BA, et al. (2018) Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity. Journal of Medicinal Chemistry
Rath CM, Benton BM, De Vicente J, et al. (2017) Optimization of CoaD inhibitors against Gram-negative organisms through targeted metabolomics. Acs Infectious Diseases
Hong S, Moritz TJ, Rath CM, et al. (2017) Assessing Antibiotic Permeability of Gram-Negative Bacteria via Nanofluidics. Acs Nano
Dovala D, Rath CM, Hu Q, et al. (2016) Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism. Proceedings of the National Academy of Sciences of the United States of America
Richie DL, Takeoka KT, Bojkovic J, et al. (2016) Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606. Plos One. 11: e0160918
Bojkovic J, Richie DL, Six DA, et al. (2015) Characterization of an Acinetobacter baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology
Dovala D, Sawyer WS, Rath CM, et al. (2015) Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system. Protein Expression and Purification
Rateb ME, Zhai Y, Ehrner E, et al. (2015) Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate. Organic & Biomolecular Chemistry. 13: 9585-92
Yang JY, Sanchez LM, Rath CM, et al. (2013) Molecular networking as a dereplication strategy. Journal of Natural Products. 76: 1686-99
Hansen DA, Rath CM, Eisman EB, et al. (2013) Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. Journal of the American Chemical Society. 135: 11232-8
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