Erika A. Taylor, Ph.D.
Affiliations: | Chemistry | Wesleyan University, Middletown, CT, United States | |
| 1998-2004 | Illinois | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
structure/function relationships and inhibitor design for enzyme-catalyzed reactionsWebsite:
http://eataylor.faculty.wesleyan.edu/Google:
"Erika A. Taylor"Mean distance: 8.78 | S | N | B | C | P |
Parents
Sign in to add mentor| John A. Gerlt | grad student | 2004 | UIUC | |
| (Characterization of ortho-succinylbenzoate synthase (OSBS): A study of mechanism, proficiency and evolutionary diversity.) | ||||
| Vern L. Schramm | post-doc | 2004-2007 | Albert Einstein | |
Children
Sign in to add trainee| Joy M Cote | grad student | Wesleyan University (Middletown, CT) | |
| Kevin P. Barry | grad student | 2007-2014 | Wesleyan University (Middletown, CT) |
| Daniel Czyzyk | grad student | 2007-2014 | Wesleyan University (Middletown, CT) |
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Publications
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| Hassan BA, Milicaj J, Tyson M, et al. (2024) In Vitro and In Silico Explorations of the Protein Conformational Changes of Corynebacterium glutamicum MshA, a Model Retaining GT-B Glycosyltransferase. Biochemistry |
| Rafalowski A, Hassan BA, Lou K, et al. (2023) How Single Amino Acid Substitutions Can Disrupt a Protein Hetero-Dimer Interface: Computational and Experimental Studies of the LigAB Dioxygenase from sp. Strain SYK-6. International Journal of Molecular Sciences. 24 |
| Hassan BA, Liu ZA, Milicaj J, et al. (2022) Kinetic Characterization and Computational Modeling of Heptosyltransferase II: Exploring the Role of Protein Dynamics in Catalysis for GT-B Glycosyltransferase. Biochemistry. 61: 1572-1584 |
| Milicaj J, Hassan BA, Cote JM, et al. (2022) Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action. Scientific Reports. 12: 7302 |
| Hassan BA, Milicaj J, Ramirez-Mondragon CA, et al. (2022) Ligand-Induced Conformational and Dynamical Changes in a GT-B Glycosyltransferase: Molecular Dynamics Simulations of Heptosyltransferase I Complexes. Journal of Chemical Information and Modeling. 62: 324-339 |
| Ramirez-Mondragon CA, Nguyen ME, Milicaj J, et al. (2021) Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics. International Journal of Molecular Sciences. 22 |
| Cote JM, Hecht CJS, Patel KR, et al. (2020) Opposites Attract: Heptosyltransferase I Conformational Changes Induced by Interactions between Substrate and Positively Charged Residues. Biochemistry |
| Wang A, Castro C, Taylor E. (2020) Inhibiting Heptosyltransferase to Combat Gram‐Negative Bacterial Infections The Faseb Journal. 34: 1-1 |
| Shukla N, Goeks J, Taylor EA, et al. (2019) Hydration Dynamics in Solutions of Cyclic Polyhydroxyl Osmolytes. The Journal of Physical Chemistry. B |
| Henry RA, Kuo YM, Siegel ZS, et al. (2019) Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems. Cells. 8 |