Jay Kalin, Ph.D.

Affiliations: 
2012 Medicinal Chemistry University of Illinois at Chicago, Chicago, IL, United States 
Area:
medicinal chemistry
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"Jay Kalin"
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Alan P. Kozikowski grad student 2012 University of Illinois, Chicago
 (Elucidation of the Histone Deacetylase 6 Pharmacophore.)
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Publications

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Anastas JN, Zee BM, Kalin JH, et al. (2019) Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell
Wu M, Hayward D, Kalin JH, et al. (2018) Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex. Elife. 7
Kalin JH, Wu M, Gomez AV, et al. (2018) Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nature Communications. 9: 53
Hsiao PY, Kalin J, Sun IH, et al. (2016) An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor. Chembiochem : a European Journal of Chemical Biology
Lu S, Zhang Y, Kalin JH, et al. (2015) Exploration of the labeling of [(11) C]tubastatin A at the hydroxamic acid site with [(11) C]carbon monoxide. Journal of Labelled Compounds & Radiopharmaceuticals
Shen S, Benoy V, Bergman JA, et al. (2015) Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease. Acs Chemical Neuroscience
Cheng F, Lienlaf M, Wang HW, et al. (2014) A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. Journal of Immunology (Baltimore, Md. : 1950). 193: 2850-62
Prusevich P, Kalin JH, Ming SA, et al. (2014) A selective phenelzine analogue inhibitor of histone demethylase LSD1. Acs Chemical Biology. 9: 1284-93
Selenica ML, Benner L, Housley SB, et al. (2014) Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition. Alzheimer's Research & Therapy. 6: 12
Chiang MJ, Holbert MA, Kalin JH, et al. (2014) An Fc domain protein-small molecule conjugate as an enhanced immunomodulator. Journal of the American Chemical Society. 136: 3370-3
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