Jay Kalin, Ph.D.

Affiliations: 
2012 Medicinal Chemistry University of Illinois at Chicago, Chicago, IL, United States 
Area:
medicinal chemistry
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"Jay Kalin"
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Alan P. Kozikowski grad student 2012 University of Illinois, Chicago
 (Elucidation of the Histone Deacetylase 6 Pharmacophore.)
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Publications

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Cheng F, Lienlaf M, Wang HW, et al. (2024) Expression of Concern: A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs. Journal of Immunology (Baltimore, Md. : 1950). 213: 1044
Padalino G, Celatka CA, Rienhoff HY, et al. (2023) Chemical modulation of lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes. Wellcome Open Research. 8: 146
Gibson F, Hanly A, Kuang K, et al. (2020) 660 Dual HDAC and LSD1 inhibition as a novel strategy to overcome BRAF inhibitor resistance Journal of Investigative Dermatology. 140
Anastas JN, Zee BM, Kalin JH, et al. (2019) Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell
Kida M, Falanga V, Wu M, et al. (2019) 941 Epigenetic manipulation of epidermal cells leads to enhanced cellular migration without an increase in cell proliferation Journal of Investigative Dermatology. 139: S162
Wu M, Hayward D, Kalin JH, et al. (2018) Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex. Elife. 7
Kalin JH, Wu M, Gomez AV, et al. (2018) Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nature Communications. 9: 53
Anastas J, Filbin M, Kim M, et al. (2018) Gene-22. Re-Programing Chromatin With A Bifunctional Lsd1/Hdac Inhibitor Induces Therapeutic Differentiation In Dipg Neuro-Oncology. 20
Wu M, Kalin J, Ryu B, et al. (2017) Abstract 5068: A novel dual action inhibitor of histone deacetylase and demethylase in melanoma Cancer Research. 77: 5068-5068
Lu S, Zhang Y, Kalin JH, et al. (2015) Exploration of the labeling of [(11) C]tubastatin A at the hydroxamic acid site with [(11) C]carbon monoxide. Journal of Labelled Compounds & Radiopharmaceuticals
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