Xiaoming Xu, Ph.D.
Affiliations: | 2008 | Chemistry | Purdue University, West Lafayette, IN, United States |
Area:
HIV-1 protease inhibitorsGoogle:
"Xiaoming Xu"Mean distance: 8.51 | S | N | B | C | P |
Parents
Sign in to add mentor| Arun K. Ghosh | grad student | 2008 | Purdue | |
| (Enantioselective total synthesis of peloruside A and spongidepsin.) | ||||
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Publications
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| Zhou Y, Xiao Y, Qiu Y, et al. (2015) Adhesion and proliferation of cells and bacteria on microchip with different surfaces microstructures. Biomedizinische Technik. Biomedical Engineering |
| Ghosh AK, Brindisi M, Yen YC, et al. (2015) Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand. Bioorganic & Medicinal Chemistry Letters. 25: 668-72 |
| Ghosh AK, Pandey S, Gangarajula S, et al. (2012) Structure-based design, synthesis, and biological evaluation of dihydroquinazoline-derived potent β-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 5460-5 |
| Nguyen TL, Xu X, Gussio R, et al. (2010) The assembly-inducing laulimalide/peloruside a binding site on tubulin: molecular modeling and biochemical studies with [³H]peloruside A. Journal of Chemical Information and Modeling. 50: 2019-28 |
| Singh AJ, Xu CX, Xu X, et al. (2010) Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity. The Journal of Organic Chemistry. 75: 2-10 |
| Ghosh AK, Kass J, Anderson DD, et al. (2008) L-selectride-mediated highly diastereoselective asymmetric reductive aldol reaction: access to an important subunit for bioactive molecules. Organic Letters. 10: 4811-4 |
| Ghosh AK, Xu X, Kim JH, et al. (2008) Enantioselective total synthesis of peloruside A: a potent microtubule stabilizer. Organic Letters. 10: 1001-4 |
| Ghosh AK, Kumaragurubaran N, Hong L, et al. (2008) Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation. Bioorganic & Medicinal Chemistry Letters. 18: 1031-6 |
| Ghosh AK, Xi K, Grum-Tokars V, et al. (2007) Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 5876-80 |
| Ghosh AK, Kumaragurubaran N, Hong L, et al. (2007) Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. Journal of Medicinal Chemistry. 50: 2399-407 |