Dianah S. Barrett, Ph.D.

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 
Area:
Chemical biology, enzymology, antibiotics, glycosyltransferases, inhibitors
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Suzanne Walker grad student 2007 Harvard
 (Characterization of peptidoglycan glycosyltransferases: Essential enzymes for bacterial cell wall biosynthesis.)
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Publications

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Barrett D, Wang TS, Yuan Y, et al. (2007) Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. The Journal of Biological Chemistry. 282: 31964-71
Yuan Y, Barrett D, Zhang Y, et al. (2007) Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 5348-53
Zhang Y, Fechter EJ, Wang TS, et al. (2007) Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan glycosyltransferases. Journal of the American Chemical Society. 129: 3080-1
Leimkuhler C, Chen L, Barrett D, et al. (2005) Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. Journal of the American Chemical Society. 127: 3250-1
Barrett D, Leimkuhler C, Chen L, et al. (2005) Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. Journal of Bacteriology. 187: 2215-7
Barrett DS, Chen L, Litterman NK, et al. (2004) Expression and characterization of the isolated glycosyltransferase module of Escherichia coli PBP1b. Biochemistry. 43: 12375-81
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