John P. Santa Maria, Ph.D.
Affiliations: | 2014 | Chemical Biology | Harvard University, Cambridge, MA, United States |
Area:
Chemical biology, enzymology, antibiotics, glycosyltransferases, inhibitorsGoogle:
"John Santa Maria"Mean distance: 9.34 | S | N | B | C | P |
Parents
Sign in to add mentor| Suzanne Walker | grad student | 2014 | Harvard | |
| (Investigating Synthetic Lethal Interactions with the Wall Teichoic Acid Pathway of Staphylococcus aureus.) | ||||
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Publications
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| Goodreid JD, Janetzko J, Santa Maria JP, et al. (2016) Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity. Journal of Medicinal Chemistry. 59: 624-46 |
| Pasquina L, Santa Maria JP, McKay Wood B, et al. (2015) A synthetic lethal approach for compound and target identification in Staphylococcus aureus. Nature Chemical Biology |
| Valentino MD, Foulston L, Sadaka A, et al. (2014) Genes contributing to Staphylococcus aureus fitness in abscess- and infection-related ecologies. Mbio. 5: e01729-14 |
| Santa Maria JP, Sadaka A, Moussa SH, et al. (2014) Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids. Proceedings of the National Academy of Sciences of the United States of America. 111: 12510-5 |
| Brown S, Santa Maria JP, Walker S. (2013) Wall teichoic acids of gram-positive bacteria. Annual Review of Microbiology. 67: 313-36 |
| Pasquina LW, Santa Maria JP, Walker S. (2013) Teichoic acid biosynthesis as an antibiotic target. Current Opinion in Microbiology. 16: 531-7 |
| Wang H, Gill CJ, Lee SH, et al. (2013) Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents. Chemistry & Biology. 20: 272-84 |
| Campbell J, Singh AK, Santa Maria JP, et al. (2011) Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus. Acs Chemical Biology. 6: 106-16 |