Joshua S. Grimley, Ph.D.
Affiliations: | 2007 | Stanford University, Palo Alto, CA |
Area:
biological chemistryGoogle:
"Joshua Grimley"Mean distance: 8.53 | S | N | B | C | P |
Parents
Sign in to add mentor| Thomas J. Wandless | grad student | 2007 | Stanford | |
| (The synthesis of FKBP ligands and the first total synthesis of phomopsin B.) | ||||
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Publications
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| Martinez RA, Stein JL, Krostag AR, et al. (2015) Genome engineering of isogenic human ES cells to model autism disorders. Nucleic Acids Research. 43: e65 |
| Grimley JS, Li L, Wang W, et al. (2013) Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16297-309 |
| Alvarez JV, Pan Tc, Ruth J, et al. (2013) Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy Cancer Cell. 24: 30-44 |
| Dvorin JD, Martyn DC, Patel SD, et al. (2010) A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science (New York, N.Y.). 328: 910-2 |
| Grimley JS, Chen DA, Banaszynski LA, et al. (2008) Synthesis and analysis of stabilizing ligands for FKBP-derived destabilizing domains Bioorganic and Medicinal Chemistry Letters. 18: 759-761 |
| Herm-Götz A, Agop-Nersesian C, Münter S, et al. (2007) Rapid control of protein level in the apicomplexan Toxoplasma gondii Nature Methods. 4: 1003-1005 |
| Grimley JS, Sawayama AM, Tanaka H, et al. (2007) The enantioselective synthesis of phomopsin B Angewandte Chemie - International Edition. 46: 8157-8159 |
| Bayle JH, Grimley JS, Stankunas K, et al. (2006) Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity. Chemistry & Biology. 13: 99-107 |
| Inoue T, Heo WD, Grimley JS, et al. (2005) An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways Nature Methods. 2: 415-418 |
| Martin MB, Sanders JM, Kendrick H, et al. (2002) Activity of bisphosphonates against Trypanosoma brucei rhodesiense. Journal of Medicinal Chemistry. 45: 2904-14 |