Stefan M. Larson, Ph.D.

Affiliations: 
2004 Stanford University, Palo Alto, CA 
Area:
theoretical methods to understand the physical properties of biological molecules
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"Stefan Larson"
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Vijay S. Pande grad student 2004 Stanford
 (Large-scale computational protein design.)
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Publications

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Zarrine-Afsar A, Larson SM, Davidson AR. (2005) The family feud: do proteins with similar structures fold via the same pathway? Current Opinion in Structural Biology. 15: 42-9
Di Nardo AA, Larson SM, Davidson AR. (2003) The relationship between conservation, thermodynamic stability, and function in the SH3 domain hydrophobic core. Journal of Molecular Biology. 333: 641-55
Larson SM, Pande VS. (2003) Sequence optimization for native state stability determines the evolution and folding kinetics of a small protein. Journal of Molecular Biology. 332: 275-86
Larson SM, Garg A, Desjarlais JR, et al. (2003) Increased detection of structural templates using alignments of designed sequences. Proteins. 51: 390-6
Pande VS, Baker I, Chapman J, et al. (2003) Atomistic protein folding simulations on the submillisecond time scale using worldwide distributed computing. Biopolymers. 68: 91-109
Larson SM, England JL, Desjarlais JR, et al. (2002) Thoroughly sampling sequence space: large-scale protein design of structural ensembles. Protein Science : a Publication of the Protein Society. 11: 2804-13
Larson SM, Ruczinski I, Davidson AR, et al. (2002) Residues participating in the protein folding nucleus do not exhibit preferential evolutionary conservation. Journal of Molecular Biology. 316: 225-33
Larson SM, Davidson AR. (2001) The identification of conserved interactions within the SH3 domain by alignment of sequences and structures. Protein Science : a Publication of the Protein Society. 9: 2170-80
Larson SM, Di Nardo AA, Davidson AR. (2000) Analysis of covariation in an SH3 domain sequence alignment: applications in tertiary contact prediction and the design of compensating hydrophobic core substitutions. Journal of Molecular Biology. 303: 433-46
Plaxco KW, Larson S, Ruczinski I, et al. (2000) Evolutionary conservation in protein folding kinetics. Journal of Molecular Biology. 298: 303-12
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