Benjamin T. Houseman, Ph.D.
Affiliations: | 2001 | University of Chicago, Chicago, IL |
Area:
chemical biology of cell adhesionGoogle:
"Benjamin Houseman"Mean distance: 7.61 | S | N | B | C | P |
Parents
Sign in to add mentor| Milan Mrksich | grad student | 2001 | Chicago | |
| (Model substrates for mechanistic studies of cell-matrix interactions.) | ||||
| Kevan Michael Shokat | post-doc | 2006-2008 | UCSF | |
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Publications
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| Diaz-Flores E, Goldschmidt H, Depeille P, et al. (2013) PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. Science Signaling. 6: ra105 |
| Cheng CK, Gustafson WC, Charron E, et al. (2012) Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 109: 12722-7 |
| Nakamura JL, Phong C, Pinarbasi E, et al. (2011) Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice. Cancer Research. 71: 106-15 |
| Fan QW, Cheng C, Hackett C, et al. (2010) Akt and autophagy cooperate to promote survival of drug-resistant glioma. Science Signaling. 3: ra81 |
| Gomez-Sjoberg R, Leyrat AA, Houseman BT, et al. (2010) Biocompatibility and reduced drug absorption of sol-gel-treated poly(dimethyl siloxane) for microfluidic cell culture applications. Analytical Chemistry. 82: 8954-60 |
| Miller S, Tavshanjian B, Oleksy A, et al. (2010) Shaping development of autophagy inhibitors with the structure of the lipid kinase Vps34. Science (New York, N.Y.). 327: 1638-42 |
| Williams O, Houseman BT, Kunkel EJ, et al. (2010) Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs. Chemistry & Biology. 17: 123-34 |
| Berndt A, Miller S, Williams O, et al. (2010) The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nature Chemical Biology. 6: 244 |
| Berndt A, Miller S, Williams O, et al. (2010) The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nature Chemical Biology. 6: 117-24 |
| Roux J, Carles M, Koh H, et al. (2010) Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. The Journal of Biological Chemistry. 285: 4278-90 |