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Amy Weeks, Ph.D.

2013 Chemistry University of California, Berkeley, Berkeley, CA 
Designing new biosynthetic pathways for in vivo cellular production of biofuels and pharmaceuticals
"Amy Weeks"

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Stuart S. Licht research assistant MIT (Neurotree)
Jennifer A. Doudna grad student 2008 UC Berkeley
Michelle C. Chang grad student 2013 UC Berkeley
 (Molecular insights into fluorine chemistry in living systems.)
James A. Wells post-doc UCSF
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Weeks AM, Wells JA. (2020) N-Terminal Modification of Proteins with Subtiligase Specificity Variants. Current Protocols in Chemical Biology. 12: e79
Weeks AM, Wells JA. (2019) Subtiligase-Catalyzed Peptide Ligation. Chemical Reviews
Weeks AM, Wang N, Pelton JG, et al. (2018) Entropy drives selective fluorine recognition in the fluoroacetyl-CoA thioesterase from. Proceedings of the National Academy of Sciences of the United States of America
Weeks AM, Wells JA. (2017) Engineering peptide ligase specificity by proteomic identification of ligation sites. Nature Chemical Biology
Lin S, Yang X, Jia S, et al. (2017) Redox-based reagents for chemoselective methionine bioconjugation. Science (New York, N.Y.). 355: 597-602
Weeks AM, Keddie NS, Wadoux RD, et al. (2014) Molecular recognition of fluorine impacts substrate selectivity in the fluoroacetyl-CoA thioesterase FlK. Biochemistry. 53: 2053-63
Weeks AM, Chang MC. (2012) Catalytic control of enzymatic fluorine specificity. Proceedings of the National Academy of Sciences of the United States of America. 109: 19667-72
Bond-Watts BB, Weeks AM, Chang MC. (2012) Biochemical and structural characterization of the trans-enoyl-CoA reductase from Treponema denticola. Biochemistry. 51: 6827-37
Walker MC, Wen M, Weeks AM, et al. (2012) Temporal and fluoride control of secondary metabolism regulates cellular organofluorine biosynthesis. Acs Chemical Biology. 7: 1576-85
Weeks AM, Chang MC. (2011) Constructing de novo biosynthetic pathways for chemical synthesis inside living cells. Biochemistry. 50: 5404-18
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