Kevin P. McCusker, Ph.D.

Affiliations: 
2009 University of California, Berkeley, Berkeley, CA, United States 
Area:
fundamental aspects of enzyme catalysis
Google:
"Kevin McCusker"
Mean distance: 8.54
 
SNBCP

Parents

Sign in to add mentor
Judith Pollock Klinman grad student 2009 UC Berkeley
 (Mechanisms of oxygen activation and coupling to carbon-hydrogen cleavage in taurine alpha-ketoglutarate dioxygenase (TauD) and active-site mutants.)
Danica G. Fujimori post-doc 2010- UCSF
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

McCusker KP, Medzihradszky KF, Shiver AL, et al. (2012) Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. Journal of the American Chemical Society. 134: 18074-81
McCusker KP, Fujimori DG. (2012) The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. Acs Chemical Biology. 7: 64-72
McCusker KP, Klinman JP. (2010) An active-site phenylalanine directs substrate binding and C-H cleavage in the α-ketoglutarate-dependent dioxygenase AauD Journal of the American Chemical Society. 132: 5114-5120
McCusker KP, Klinman JP. (2009) Modular behavior of tauD provides insight into the origin of specificity in α-ketoglutarate-dependent nonheme iron oxygenases Proceedings of the National Academy of Sciences of the United States of America. 106: 19791-19795
McCusker KP, Klinman JP. (2009) Facile synthesis of 1,1-[2H2]-2-methylaminoethane-1-sulfonic acid as a substrate for taurine α ketoglutarate dioxygenase (TauD) Tetrahedron Letters. 50: 611-613
Mirica LM, McCusker KP, Munos JW, et al. (2008) 18O kinetic isotope effects in non-heme iron enzymes: probing the nature of Fe/O2 intermediates. Journal of the American Chemical Society. 130: 8122-3
Thrower J, Mirica LM, McCusker KP, et al. (2006) Mechanistic investigations of 1-aminocyclopropane 1-carboxylic acid oxidase with alternate cyclic and acyclic substrates. Biochemistry. 45: 13108-17
See more...