Zachary D. Nagel, Ph.D.
Affiliations: | 2009 | University of California, Berkeley, Berkeley, CA, United States |
Area:
fundamental aspects of enzyme catalysisGoogle:
"Zachary Nagel"Mean distance: 8.54 | S | N | B | C | P |
Parents
Sign in to add mentor| Judith Pollock Klinman | grad student | 2009 | UC Berkeley | |
| (A role for nuclear tunneling and protein dynamics in enzyme catalysis.) | ||||
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Publications
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| Koyen AE, Madden MZ, Park D, et al. (2020) EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair. Oncogene |
| Lee KJ, Piett CG, Andrews JF, et al. (2019) Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer. Plos One. 14: e0223725 |
| Chan EM, Shibue T, McFarland JM, et al. (2019) WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature |
| Nagel ZD, Beharry AA, Mazzucato P, et al. (2019) Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells. Plos One. 14: e0208341 |
| Moore S, Berger ND, Luijsterburg MS, et al. (2019) The CHD6 chromatin remodeler is an oxidative DNA damage response factor. Nature Communications. 10: 241 |
| Russo M, Crisafulli G, Sogari A, et al. (2019) Abstract A120: Adaptive mutability of colorectal cancers in response to targeted therapies Molecular Cancer Therapeutics. 18 |
| Parrish MC, Chaim IA, Nagel ZD, et al. (2018) Nitric oxide induced S-nitrosation causes base excision repair imbalance. Dna Repair. 68: 25-33 |
| Shen J, Ju Z, Zhao W, et al. (2018) ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade. Nature Medicine |
| Chaim IA, Nagel ZD, Jordan JJ, et al. (2017) In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities. Proceedings of the National Academy of Sciences of the United States of America |
| Nagel ZD, Kitange GJ, Gupta SK, et al. (2016) DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme. Cancer Research |