Michelle M. Spiering, Ph.D.

Affiliations: 
2002 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
catalytic and biological properties of redox enzymes
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Parents

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Michael A. Marletta grad student 2002 University of Michigan
 (The deactivation of diptheria toxin repressor by nitric oxide.)
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Publications

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Feng X, Spiering MM, de Luna Almeida Santos R, et al. (2023) Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nature Communications. 14: 4396
Feng X, Spiering MM, de Luna Almeida Santos R, et al. (2023) Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Biorxiv : the Preprint Server For Biology
Ding F, Cocco S, Raj S, et al. (2022) Displacement and dissociation of oligonucleotides during DNA hairpin closure under strain. Nucleic Acids Research
Benkovic SJ, Spiering MM. (2017) Understanding DNA replication by the bacteriophage T4 replisome. The Journal of Biological Chemistry
Spiering MM, Hanoian P, Gannavaram S, et al. (2017) RNA primer-primase complexes serve as the signal for polymerase recycling and Okazaki fragment initiation in T4 phage DNA replication. Proceedings of the National Academy of Sciences of the United States of America
Talukder P, Chen S, Roy B, et al. (2015) Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA-Protein Interaction. Biochemistry
Noble E, Spiering MM, Benkovic SJ. (2015) Coordinated DNA Replication by the Bacteriophage T4 Replisome. Viruses. 7: 3186-200
Zhao Y, Chen D, Yue H, et al. (2014) Dark-field illumination on zero-mode waveguide/microfluidic hybrid chip reveals T4 replisomal protein interactions. Nano Letters. 14: 1952-60
Sengupta S, Spiering MM, Dey KK, et al. (2014) DNA polymerase as a molecular motor and pump. Acs Nano. 8: 2410-8
Chen D, Yue H, Spiering MM, et al. (2013) Insights into Okazaki fragment synthesis by the T4 replisome: the fate of lagging-strand holoenzyme components and their influence on Okazaki fragment size. The Journal of Biological Chemistry. 288: 20807-16
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