Jonathan A. Winger, Ph.D.

Affiliations: 
2004 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
catalytic and biological properties of redox enzymes
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Parents

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Michael A. Marletta grad student 2004 University of Michigan
 (Activation and deactivation of soluble guanylate cyclase: Domain organization and the requirement for non-heme equivalents of nitric oxide.)
John Kuriyan post-doc UC Berkeley
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Publications

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Boehme J, Le Moan N, Kameny RJ, et al. (2019) Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. Plos Biology. 17: e3000119
Boehme J, Le Moan N, Kameny RJ, et al. (2018) Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. Plos Biology. 16: e2005924
Moan NL, Leung P, Ng S, et al. (2018) Abstract 4726A: The oxygen carrier omx restores antitumor immunity and cures tumors as a single agent or in combination with checkpoint inhibitors in an intracranial glioblastoma mouse model Cancer Research. 78
Leong KG, Pan Y, Guo C, et al. (2018) Abstract 1744: Reversal of advanced colitis-associated colon cancer by OMX, a novel oxygen carrier that immunosensitizes the hypoxic tumor microenvironment Immunology. 78: 1744-1744
Le Moan N, Davis T, Leung P, et al. (2018) TMIC-15. OMX IS A TUMOR MICROENVIRONMENT MODIFIER THAT RESTORES ANTI-TUMOR IMMUNITY AND IMPROVES ANTI-TUMOR EFFICACY BY REDUCING TUMOR HYPOXIA IN INTRACRANIAL GLIOBLASTOMA MOUSE MODEL Neuro-Oncology. 20: vi259-vi259
Leong KG, Pan Y, Winger JA, et al. (2017) Abstract 1627: Enhancement of anti-cancer immunity by OMX, a novel oxygen carrier immunotherapeutic that ameliorates the hypoxic tumor microenvironment Cancer Research. 77: 1627-1627
Visperas PR, Wilson CG, Winger JA, et al. (2016) Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. Journal of Biomolecular Screening
Krtolica A, Moan NL, Leung P, et al. (2016) Abstract 2790: Sensitizing the hypoxic tumor microenvironment with OMX, a breakthrough oxygen delivery protein: From protein engineering to clinical trial Cancer Research. 76: 2790-2790
Moan NL, Leung P, Bedard C, et al. (2016) IMST-52. OMX, AN IND-STAGE BROAD-ACTING OXYGEN CARRIER, IMMUNOSENSITIZES THE TUMOR MICROENVIRONMENT AND PROMOTES EFFECTOR T CELL RESPONSES IN THE GL261 INTRACRANIAL SYNGENEIC GLIOBLASTOMA MODEL Neuro-Oncology. 18: vi98-vi98
Visperas PR, Winger JA, Horton TM, et al. (2015) Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. The Biochemical Journal. 465: 149-61
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