Zachary E. Newby, Ph.D.

Affiliations: 
2008 Chemistry and Chemical Biology University of California, San Francisco, San Francisco, CA 
Area:
membrane protein characterizations and crystal structures
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"Zachary Newby"
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Parents

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David Julius grad student 2008 UCSF (Neurotree)
 (The pursuit of membrane protein structures and the malarial aquaglyceroporin pfAQP.)
Robert M. Stroud grad student 2008 UCSF
 (The pursuit of membrane protein structures and the malarial aquaglyceroporin pfAQP.)
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Publications

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Newby ZE, O'Connell JD, Gruswitz F, et al. (2009) A general protocol for the crystallization of membrane proteins for X-ray structural investigation. Nature Protocols. 4: 619-37
Newby ZE, O'Connell J, Robles-Colmenares Y, et al. (2008) Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum. Nature Structural & Molecular Biology. 15: 619-25
Savage DF, Anderson CL, Robles-Colmenares Y, et al. (2007) Cell-free complements in vivo expression of the E. coli membrane proteome. Protein Science : a Publication of the Protein Society. 16: 966-76
Newby Z, Lee TT, Morse RJ, et al. (2006) The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 45: 7415-28
Hur S, Newby ZE, Bruice TC. (2004) Transition state stabilization by general acid catalysis, water expulsion, and enzyme reorganization in Medicago savita chalcone isomerase. Proceedings of the National Academy of Sciences of the United States of America. 101: 2730-5
Newby ZE, Lau EY, Bruice TC. (2002) A theoretical examination of the factors controlling the catalytic efficiency of the DNA-(adenine-N6)-methyltransferase from Thermus aquaticus. Proceedings of the National Academy of Sciences of the United States of America. 99: 7922-7
Lau EY, Newby ZE, Bruice TC. (2001) A theoretical examination of the acid-catalyzed and noncatalyzed ring-opening reaction of an oxirane by nucleophilic addition of acetate. Implications to epoxide hydrolases. Journal of the American Chemical Society. 123: 3350-7
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