Olusegun Williams, Ph.D.
Affiliations: | 2011 | Chemistry and Chemical Biology | University of California, San Francisco, San Francisco, CA |
Area:
signal transduction pathways in cells and whole organismsGoogle:
"Olusegun Williams"Mean distance: 8.45 | S | N | B | C | P |
Parents
Sign in to add mentor| Kevan Michael Shokat | grad student | 2006-2011 | UCSF | |
| (Discovery and development of dual PI3Kdelta/gamma inhibitors for use as novel anti-inflammatory agents.) | ||||
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Publications
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| Diaz-Flores E, Goldschmidt H, Depeille P, et al. (2013) PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. Science Signaling. 6: ra105 |
| Williams O, Houseman BT, Kunkel EJ, et al. (2010) Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs. Chemistry & Biology. 17: 123-34 |
| Berndt A, Miller S, Williams O, et al. (2010) The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nature Chemical Biology. 6: 244 |
| Berndt A, Miller S, Williams O, et al. (2010) The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nature Chemical Biology. 6: 117-24 |
| Sly LM, Hamilton MJ, Kuroda E, et al. (2009) SHIP prevents lipopolysaccharide from triggering an antiviral response in mice. Blood. 113: 2945-54 |
| Wang J, Knight ZA, Fiedler D, et al. (2008) Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport. American Journal of Physiology. Renal Physiology. 295: F843-50 |
| Knight ZA, Gonzalez B, Feldman ME, et al. (2006) A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 125: 733-47 |