Gregory S. Ducker, Ph.D.

Affiliations: 
2013 Chemistry University of California, Berkeley, Berkeley, CA 
Area:
signal transduction pathways in cells and whole organisms
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Parents

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Joseph Walter Chihade research assistant 2004-2006 Carleton College
Kevan Michael Shokat grad student 2008-2013 UC Berkeley
 (Primary resistance to ATP-competitive mTOR inhibitors for the treatment of solid tumors.)
Joshua D. Rabinowitz post-doc 2013- Princeton
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Publications

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Rodriguez AE, Ducker GS, Billingham LK, et al. (2019) Serine Metabolism Supports Macrophage IL-1β Production. Cell Metabolism
Chamberlain CE, German MS, Yang K, et al. (2018) A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-Resistant Tumors. Molecular Cancer Therapeutics
Rodan LH, Qi W, Ducker GS, et al. (2018) 5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Molecular Genetics and Metabolism
Ksionda O, Mues M, Wandler AM, et al. (2018) Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy. Plos One. 13: e0193849
Morscher RJ, Ducker GS, Li SH, et al. (2018) Mitochondrial translation requires folate-dependent tRNA methylation. Nature
Ducker GS, Ghergurovich JM, Mainolfi N, et al. (2017) Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 114: 11404-11409
Chen L, Ducker GS, Lu W, et al. (2017) An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate. Analytical and Bioanalytical Chemistry
Ducker GS, Chen L, Morscher RJ, et al. (2016) Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism. 24: 640-641
Ducker GS, Rabinowitz JD. (2016) One-Carbon Metabolism in Health and Disease. Cell Metabolism
Ducker GS, Chen L, Morscher RJ, et al. (2016) Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism
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