Gregory S. Ducker, Ph.D.
Affiliations: | 2013 | Chemistry | University of California, Berkeley, Berkeley, CA, United States |
Area:
signal transduction pathways in cells and whole organismsGoogle:
"Gregory Ducker"Mean distance: 8.45
Parents
Sign in to add mentor| Joseph Walter Chihade | research assistant | 2004-2006 | Carleton College | |
| Kevan Michael Shokat | grad student | 2008-2013 | UC Berkeley | |
| (Primary resistance to ATP-competitive mTOR inhibitors for the treatment of solid tumors.) | ||||
| Joshua D. Rabinowitz | post-doc | 2013- | Princeton | |
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Publications
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| Dunlap KN, Bender A, Bowles A, et al. (2025) SLC7A5 is required for cancer cell growth under arginine-limited conditions. Cell Reports. 44: 115130 |
| Lee HM, Muhammad N, Lieu EL, et al. (2024) Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer. Nature Metabolism |
| McBride MJ, Hunter CJ, Zhang Z, et al. (2024) Glycine homeostasis requires reverse SHMT flux. Cell Metabolism. 36: 103-115.e4 |
| Dekhne AS, Shah K, Ducker GS, et al. (2023) Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy. Molecular Cancer Therapeutics. OF1 |
| Panic V, Pearson S, Banks J, et al. (2020) Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis. Elife. 9 |
| García-Cañaveras JC, Lancho O, Ducker GS, et al. (2020) SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia |
| Li AM, Ducker GS, Li Y, et al. (2020) Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR |
| Li AM, Ducker GS, Li Y, et al. (2020) Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713 |
| Kuramoto J, Smith R, Kalasekar SM, et al. (2020) Abstract 3740: Role of phosphatidylcholine in β-catenin-driven hepatocellular carcinoma Cancer Research. 80: 3740-3740 |
| Bensard CL, Wisidigama DR, Olson KA, et al. (2019) Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. Cell Metabolism |