Christopher L. Cioffi, Ph.D.

Affiliations: 
2000 Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Medications to Treat Addictive Disorders
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"Christopher Cioffi"
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Dinah Thiers Farrington grad student RPI
Mark P. Wentland grad student 2000 RPI
 (The synthesis of novel 2,6-methano-3-benzazocin-8-amines and synthetic studies directed toward FR-900482.)
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Publications

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Mostyn SN, Sarker S, Muthuraman P, et al. (2020) A photoswitchable ORG25543 congener enables optical control of glycine transporter 2. Acs Chemical Neuroscience
Ma Z, King K, Alqahtani M, et al. (2019) Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis. Plos One. 14: e0224094
Shin Y, Moiseyev G, Petrukhin K, et al. (2018) A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration. Biochimica Et Biophysica Acta
Cioffi CL, Liu S, Wolf MA, et al. (2016) Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1. Journal of Medicinal Chemistry
Cioffi CL, Racz B, Freeman EE, et al. (2015) Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease. Journal of Medicinal Chemistry
Cioffi CL, Dobri N, Freeman EE, et al. (2014) Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease. Journal of Medicinal Chemistry. 57: 7731-57
Cioffi CL, Wolf MA, Guzzo PR, et al. (2013) Design, synthesis, and SAR of N-((1-(4-(propylsulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide inhibitors of glycine transporter-1. Bioorganic & Medicinal Chemistry Letters. 23: 1257-61
Manning DD, Cioffi CL, Usyatinsky A, et al. (2011) Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. Bioorganic & Medicinal Chemistry Letters. 21: 58-61
Cioffi CL, Lansing JJ, Yüksel H. (2010) Synthesis of 2-aminobenzoxazoles using tetramethyl orthocarbonate or 1,1-dichlorodiphenoxymethane Journal of Organic Chemistry. 75: 7942-7945
Cioffi CL, Liu S, Wolf MA. (2010) Recent Developments in Glycine Transporter-1 Inhibitors Annual Reports in Medicinal Chemistry. 45: 19-35
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