Christopher L. Cioffi, Ph.D.
Affiliations: | 2000 | Rensselaer Polytechnic Institute, Troy, NY, United States |
Area:
Medications to Treat Addictive DisordersGoogle:
"Christopher Cioffi"Mean distance: 10.02 | S | N | B | C | P |
Parents
Sign in to add mentorDinah Thiers Farrington | grad student | RPI | ||
Mark P. Wentland | grad student | 2000 | RPI | |
(The synthesis of novel 2,6-methano-3-benzazocin-8-amines and synthetic studies directed toward FR-900482.) |
Collaborators
Sign in to add collaboratorSubhodeep Sarker | collaborator | 2018- | Albany College of Pharmacy and Health Sciences (Neurotree) |
BETA: Related publications
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Publications
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Gallagher CI, Frangos ZJ, Sheipouri D, et al. (2023) Novel Phenylene Lipids That Are Positive Allosteric Modulators of Glycine Receptors and Inhibitors of Glycine Transporter 2. Acs Chemical Neuroscience |
Cioffi CL, Muthuraman P, Raja A, et al. (2020) Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities. Journal of Medicinal Chemistry |
Mostyn SN, Sarker S, Muthuraman P, et al. (2020) A photoswitchable ORG25543 congener enables optical control of glycine transporter 2. Acs Chemical Neuroscience |
Cioffi CL, Racz B, Váradi A, et al. (2019) Design, Synthesis, and Pre-Clinical Efficacy of Novel Non-Retinoid Antagonists of Retinol Binding Protein 4 in the Mouse Model of Hepatic Steatosis. Journal of Medicinal Chemistry |
Racz B, Varadi A, Kong J, et al. (2018) A non-retinoid antagonist of Retinol-Binding Protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle. The Journal of Biological Chemistry |
Cioffi CL. (2018) Glycine transporter-1 inhibitors: a patent review (2011 - 2016). Expert Opinion On Therapeutic Patents |
Cioffi CL. (2017) Modulation of Glycine-Mediated Spinal Neurotransmission for the Treatment of Chronic Pain. Journal of Medicinal Chemistry |
Cioffi CL, Liu S, Wolf MA, et al. (2016) Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1. Journal of Medicinal Chemistry |
Sakthivel P, Sharma N, Klahn P, et al. (2016) Inhibitors of Glycine Transporter-1: Potential Therapeutics for the Treatment of CNS Disorders. Current Topics in Medicinal Chemistry |
Cioffi CL, Racz B, Freeman EE, et al. (2015) Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease. Journal of Medicinal Chemistry |