Melisa Ruiz-Gutierrez, Ph.D.
Affiliations: | 2007 | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
Area:
molecular basis of cancerGoogle:
"Melisa Ruiz-Gutierrez"Mean distance: 9.75 | S | N | B | C | P |
Parents
Sign in to add mentor| Katherine L.B. Borden | grad student | 2007 | Mount Sinai School of Medicine | |
| (Composition and regulation of nuclear eIF4E ribonucleoprotein complexes.) | ||||
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Publications
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| Joyce CE, Saadatpour A, Ruiz-Gutierrez M, et al. (2019) TGFβ signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome. The Journal of Clinical Investigation. 130 |
| Ruiz-Gutierrez M, Vargel Bölükbaşi Ö, Alexe G, et al. (2019) Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells. Jci Insight. 5 |
| Burwick N, Zhang MY, de la Puente P, et al. (2017) The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma. Leukemia Research. 55: 23-32 |
| Joyce C, Saadatpour A, Jiang L, et al. (2016) Single Cell Transcriptional Profiling Reveals Activation of TNF-Alpha Signaling in Hematopoietic Stem and Progenitor Cells from Shwachman-Diamond Syndrome Patients Blood. 128: 335-335 |
| Ruiz-Gutierrez M, Vargel Bolukbasi O, Vo L, et al. (2016) Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells Blood. 128: 1496-1496 |
| Culjkovic B, Topisirovic I, Skrabanek L, et al. (2006) eIF4E is a central node of an RNA regulon that governs cellular proliferation Journal of Cell Biology. 175: 415-426 |
| Culjkovic B, Topisirovic I, Skrabanek L, et al. (2005) eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′UTR Journal of Cell Biology. 169: 245-256 |
| Topisirovic I, Ruiz-Gutierrez M, Borden KLB. (2004) Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities Cancer Research. 64: 8639-8642 |