Adi D. Dubash, Ph.D.
Affiliations: | 2009 | Cell & Developmental Biology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Cytoskeleton, Focal AdhesionsGoogle:
"Adi Dubash"Mean distance: 9.79 | S | N | B | C | P |
Parents
Sign in to add mentor| Keith Burridge | grad student | 2009 | UNC Chapel Hill | |
| (Regulation of RhoA GTPase signaling by guanine nucleotide exchange factors in response to extracellular matrix adhesion and DNA damage.) | ||||
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Publications
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| Shelton WT, Thomas SM, Alexander HR, et al. (2021) Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Scientific Reports. 11: 13295 |
| Godwin A, Eldredge L, Dubash AD. (2020) The MAL/SRF Pathway Regulates Desmosome Protein Expression and Localization in Cancer Cells The Faseb Journal. 34: 1-1 |
| Alexander H, Conway D, Dubash AD. (2020) Regulation of Extracellular Matrix Gene Expression by Desmosomal Cadherins The Faseb Journal. 34: 1-1 |
| Bendrick JL, Eldredge LA, Williams EI, et al. (2018) Desmoplakin harnesses Rho GTPase and p38 MAPK signaling to coordinate cellular migration. The Journal of Investigative Dermatology |
| Kam CY, Dubash AD, Magistrati E, et al. (2018) Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. The Journal of Cell Biology |
| Dubash AD, Kam CY, Aguado BA, et al. (2016) Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes. The Journal of Cell Biology |
| Patel DM, Dubash AD, Kreitzer G, et al. (2014) Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions. The Journal of Cell Biology. 206: 779-97 |
| Dubash AD, Koetsier JL, Amargo EV, et al. (2013) The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1. The Journal of Cell Biology. 202: 653-66 |
| Harmon RM, Simpson CL, Johnson JL, et al. (2013) Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. The Journal of Clinical Investigation. 123: 1556-70 |
| Guilluy C, Dubash AD, García-Mata R. (2011) Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus. Nature Protocols. 6: 2050-60 |