Adi D. Dubash, Ph.D.

Affiliations: 
2009 Cell & Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cytoskeleton, Focal Adhesions
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Parents

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Keith Burridge grad student 2009 UNC Chapel Hill
 (Regulation of RhoA GTPase signaling by guanine nucleotide exchange factors in response to extracellular matrix adhesion and DNA damage.)
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Publications

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Dubash AD, Kam CY, Aguado BA, et al. (2016) Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes. The Journal of Cell Biology
Patel DM, Dubash AD, Kreitzer G, et al. (2014) Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions. The Journal of Cell Biology. 206: 779-97
Moy I, Todorovi? V, Dubash AD, et al. (2014) Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells Oncogene
Dubash AD, Koetsier JL, Amargo EV, et al. (2013) The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1. The Journal of Cell Biology. 202: 653-66
Harmon RM, Simpson CL, Johnson JL, et al. (2013) Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. The Journal of Clinical Investigation. 123: 1556-70
Guilluy C, Dubash AD, García-Mata R. (2011) Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus. Nature Protocols. 6: 2050-60
Dubash AD, Green KJ. (2011) Desmosomes. Current Biology : Cb. 21: R529-31
Dubash AD, Guilluy C, Srougi MC, et al. (2011) The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals. Plos One. 6: e17380
Todorović V, Desai BV, Patterson MJ, et al. (2010) Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling. Journal of Cell Science. 123: 3576-86
Medlin MD, Staus DP, Dubash AD, et al. (2010) Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1779-86
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