Ryan A. Mehl, Ph.D.

Affiliations: 
2001 Cornell University, Ithaca, NY, United States 
Area:
Barton Professor of Chemistry
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Parents

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Tadhg P. Begley grad student 2001 Cornell
 (Mechanistic studies on the formation and repair of a novel DNA lesion: The spore photoproduct. Studies on the first in vitro biosynthesis of thiamin from purine precursors.)
Peter G. Schultz post-doc 2004- Scripps Research Institute
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Publications

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Eddins AJ, Pung AH, Cooley RB, et al. (2024) Tetrazine Amino Acid Encoding for Rapid and Complete Protein Bioconjugation. Bio-Protocol. 14: e5048
Allen MC, Karplus PA, Mehl RA, et al. (2024) Genetic Encoding of Phosphorylated Amino Acids into Proteins. Chemical Reviews
Eddins AJ, Bednar RM, Jana S, et al. (2023) Truncation-Free Genetic Code Expansion with Tetrazine Amino Acids for Quantitative Protein Ligations. Bioconjugate Chemistry
Bednar RM, Karplus PA, Mehl RA. (2023) Site-specific dual encoding and labeling of proteins via genetic code expansion. Cell Chemical Biology
Galles GD, Infield DT, Clark CJ, et al. (2023) Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells. Nature Communications. 14: 59
Zhu P, Franklin R, Vogel A, et al. (2021) PermaPhos : autonomous synthesis of functional, permanently phosphorylated proteins. Biorxiv : the Preprint Server For Biology
Bednar RM, Jana S, Kuppa S, et al. (2021) Genetic Incorporation of Two Mutually Orthogonal Bioorthogonal Amino Acids That Enable Efficient Protein Dual-Labeling in Cells. Acs Chemical Biology
Galles GD, Infield DT, Mehl RA, et al. (2021) Selection and validation of orthogonal tRNA/synthetase pairs for the encoding of unnatural amino acids across kingdoms. Methods in Enzymology. 654: 3-18
Jang HS, Gu X, Cooley RB, et al. (2020) Correction to Efficient Site-Specific Prokaryotic and Eukaryotic Incorporation of Halotyrosine Amino Acids into Proteins. Acs Chemical Biology
Oscar BG, Zhu L, Wolfendeen H, et al. (2020) Dissecting Optical Response and Molecular Structure of Fluorescent Proteins With Non-canonical Chromophores. Frontiers in Molecular Biosciences. 7: 131
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