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Tathagata Mukherjee, Ph.D.

Affiliations: 
2009 Cornell University, Ithaca, NY, United States 
Area:
Barton Professor of Chemistry
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"Tathagata Mukherjee"
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Tadhg P. Begley grad student 2009 Cornell
 (Mechanistic studies on tryptophan 2,3-dioxygenase, and characterization of genes involved in vitamin B6 and pyrimidine catabolism.)

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Publications

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Mashalidis EH, Mukherjee T, Sledź P, et al. (2011) Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity. Plos One. 6: e27643
Mukherjee T, Hanes J, Tews I, et al. (2011) Pyridoxal phosphate: biosynthesis and catabolism. Biochimica Et Biophysica Acta. 1814: 1585-96
Mukherjee T, Zhang Y, Abdelwahed S, et al. (2010) Catalysis of a flavoenzyme-mediated amide hydrolysis. Journal of the American Chemical Society. 132: 5550-1
McCulloch KM, Mukherjee T, Begley TP, et al. (2010) Structure determination and characterization of the vitamin B6 degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase. Biochemistry. 49: 1226-35
Mukherjee T, McCulloch KM, Ealick SE, et al. (2010) Cofactor catabolism Comprehensive Natural Products Ii: Chemistry and Biology. 7: 649-674
McCulloch KM, Mukherjee T, Begley TP, et al. (2009) Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications. Biochemistry. 48: 4139-49
Mukherjee T, Hilmey DG, Begley TP. (2008) PLP catabolism: identification of the 2-(Acetamidomethylene)succinate hydrolase gene in Mesorhizobium loti MAFF303099. Biochemistry. 47: 6233-41
Mukherjee T, McCulloch KM, Ealick SE, et al. (2007) Gene identification and structural characterization of the pyridoxal 5'-phosphate degradative protein 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase from mesorhizobium loti MAFF303099. Biochemistry. 46: 13606-15
Mukherjee T, Kinsland C, Begley TP. (2007) PLP catabolism: identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099. Bioorganic Chemistry. 35: 458-64
Zhang Y, Kang SA, Mukherjee T, et al. (2007) Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis. Biochemistry. 46: 145-55
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