Jason G. McCoy, Ph.D.

Affiliations: 
2006 University of Wisconsin, Madison, Madison, WI 
Area:
Biochemistry, X-ray diffraction, computational biology
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"Jason McCoy"
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Parents

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Ming Zhou grad student UW Madison
George N. Phillips grad student 2006 UW Madison
 (Structure -function relationships in structural genomics targets.)
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Publications

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Ren Z, Lee J, Moosa MM, et al. (2018) Structure of an EIIC sugar transporter trapped in an inward-facing conformation. Proceedings of the National Academy of Sciences of the United States of America
McCoy JG, Ren Z, Stanevich V, et al. (2016) The Structure of a Sugar Transporter of the Glucose EIIC Superfamily Provides Insight into the Elevator Mechanism of Membrane Transport. Structure (London, England : 1993)
Bai Y, McCoy JG, Levin EJ, et al. (2015) X-ray structure of a mammalian stearoyl-CoA desaturase. Nature
McCoy JG, Levin EJ, Zhou M. (2015) Structural insight into the PTS sugar transporter EIIC. Biochimica Et Biophysica Acta. 1850: 577-585
McCoy JG, Rusinova R, Kim DM, et al. (2014) A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics. The Journal of Biological Chemistry. 289: 9535-46
Zhou X, Levin EJ, Pan Y, et al. (2014) Structural basis of the alternating-access mechanism in a bile acid transporter. Nature. 505: 569-73
Posson DJ, Thompson AN, McCoy JG, et al. (2013) Molecular interactions involved in proton-dependent gating in KcsA potassium channels. The Journal of General Physiology. 142: 613-24
Posson DJ, McCoy JG, Nimigean CM. (2013) The voltage-dependent gate in MthK potassium channels is located at the selectivity filter. Nature Structural & Molecular Biology. 20: 159-66
Bailey LJ, Acheson JF, McCoy JG, et al. (2012) Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 51: 1101-13
McCoy JG, Nimigean CM. (2012) Structural correlates of selectivity and inactivation in potassium channels. Biochimica Et Biophysica Acta. 1818: 272-85
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