Devin T. Wiley, Ph.D.

Affiliations: 
2013 Chemical Engineering California Institute of Technology, Pasadena, CA 
Area:
Catalysis, Molecular Therapy
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Mark E. Davis grad student 2013 Caltech
 (Design of Nanoparticles That Cross the Blood-Brain Barrier by Receptor Mediated Transcytosis.)
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Publications

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Chao J, Lin J, Frankel P, et al. (2017) Pilot trial of CRLX101 in patients with advanced, chemotherapy-refractory gastroesophageal cancer. Journal of Gastrointestinal Oncology. 8: 962-969
Clark AJ, Wiley DT, Zuckerman JE, et al. (2016) CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing. Proceedings of the National Academy of Sciences of the United States of America
Chao J, Lin J, Frankel PH, et al. (2016) Pilot trial of CRLX101 in patients (pts) with advanced, chemotherapy-refractory gastroesophageal cancer (GEC). Journal of Clinical Oncology. 34: 44-44
Clark A, Wiley DT, Zuckerman JE, et al. (2015) Abstract B33: CRLX101, an investigational nanoparticle-drug conjugate, localizes in human tumors and not in adjacent healthy tissue after intravenous dosing Molecular Cancer Therapeutics. 14
Eliasof S, Lazarus D, Peters CG, et al. (2013) Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle. Proceedings of the National Academy of Sciences of the United States of America. 110: 15127-32
Wiley DT, Webster P, Gale A, et al. (2013) Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor. Proceedings of the National Academy of Sciences of the United States of America. 110: 8662-7
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