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Kaycie M. Deyle, Ph.D.

Affiliations: 
2014 Chemistry California Institute of Technology, Pasadena, CA 
Area:
solid-state quantum physics, materials science, basic surface science, Microfluidics-based assays of blood proteins, artificial antibodies
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"Kaycie Deyle"
Mean distance: 8.68
 		SNBCP
Cross-listing: Materials Tree

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James Richard Heath grad student 2014 Caltech
 (Development of Protein-Catalyzed Capture (PCC) Agents with Application to the Specific Targeting of the E17K Point Mutation of Akt1.)

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Mothukuri GK, Kale SS, Stenbratt CL, et al. (2020) Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries. Chemical Science. 11: 7858-7863
Wilbs J, Kong XD, Middendorp SJ, et al. (2020) Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs. Nature Communications. 11: 3890
Kong X, Moriya J, Carle V, et al. (2020) De novo development of proteolytically resistant therapeutic peptides for oral administration Nature Biomedical Engineering. 4: 560-571
Mothukuri GK, Kale SS, Stenbratt CL, et al. (2020) Macrocycle synthesis strategy based on step-wise “adding and reacting” three components enables screening of large combinatorial libraries Chemical Science. 11: 7858-7863
Kale SS, Bergeron-Brlek M, Wu Y, et al. (2019) Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands. Science Advances. 5: eaaw2851
Maola K, Wilbs J, Touati J, et al. (2019) Engineered Peptide Macrocycles Can Inhibit Matrix Metalloproteinases with High Selectivity Angewandte Chemie. 58: 11801-11805
Deyle K, Heinis C. (2018) Drugs Based on de novo-developed Peptides are Coming of Age mune is a. Chimia. 72: 426-427
Farrow B, Hong SA, Romero EC, et al. (2018) Correction to A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen. Acs Nano
Kale SS, Villequey C, Kong XD, et al. (2018) Cyclization of peptides with two chemical bridges affords large scaffold diversities. Nature Chemistry
Farrow B, Wong M, Malette J, et al. (2018) Corrigendum: Epitope Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent In-Cell Inhibitor of Botulinum Neurotoxin. Angewandte Chemie (International Ed. in English). 57: 1439
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