Arpita Agrawal, Ph.D.

Affiliations: 
2011 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Bioinorganic and coordination chemistry. Metalloprotein inhibitors and supramolecular materials
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"Arpita Agrawal"
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Seth M. Cohen grad student 2011 UCSD
 (The Importance of Metal Binding in Metalloprotein Inhibitors.)
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Publications

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Daniel KB, Agrawal A, Manchester M, et al. (2013) Readily accessible fluorescent probes for sensitive biological imaging of hydrogen peroxide. Chembiochem : a European Journal of Chemical Biology. 14: 593-8
Garner AL, Struss AK, Fullagar JL, et al. (2012) 3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB. Acs Medicinal Chemistry Letters. 3: 668-672
Agrawal A, DeSoto J, Fullagar JL, et al. (2012) Probing chelation motifs in HIV integrase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 109: 2251-6
Christianson CA, Fitzsimmons BL, Shim JH, et al. (2012) Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a tumor necrosis factor-dependent mechanism. Neuroscience. 200: 199-210
Johnson S, Barile E, Farina B, et al. (2011) Targeting metalloproteins by fragment-based lead discovery. Chemical Biology & Drug Design. 78: 211-23
Schulze Wischeler J, Innocenti A, Vullo D, et al. (2010) Bidentate Zinc chelators for alpha-carbonic anhydrases that produce a trigonal bipyramidal coordination geometry. Chemmedchem. 5: 1609-15
Rouffet M, de Oliveira CA, Udi Y, et al. (2010) From sensors to silencers: quinoline- and benzimidazole-sulfonamides as inhibitors for zinc proteases. Journal of the American Chemical Society. 132: 8232-3
Agrawal A, Johnson SL, Jacobsen JA, et al. (2010) Chelator fragment libraries for targeting metalloproteinases. Chemmedchem. 5: 195-9
Romero-Perez D, Agrawal A, Jacobsen J, et al. (2009) Effects of novel semiselective matrix metalloproteinase inhibitors on ex vivo cardiac structure-function. Journal of Cardiovascular Pharmacology. 53: 452-61
Agrawal A, de Oliveira CA, Cheng Y, et al. (2009) Thioamide hydroxypyrothiones supersede amide hydroxypyrothiones in potency against anthrax lethal factor. Journal of Medicinal Chemistry. 52: 1063-74
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