Randy F. Gastwirt, Ph.D.

Affiliations: 
2008 Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
Fibroblast Growth Factor Receptors (FGFRs) in Human Cancer
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"Randy Gastwirt"
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Daniel J. Donoghue grad student 2008 UCSD
 (Spy1 regulation of the cell cycle, checkpoint activation, and apoptosis.)
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Publications

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McAndrew CW, Gastwirt RF, Donoghue DJ. (2009) The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis. Cell Cycle (Georgetown, Tex.). 8: 66-75
McAndrew CW, Gastwirt RF, Meyer AN, et al. (2007) Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27. Cell Cycle (Georgetown, Tex.). 6: 1937-45
Gastwirt RF, McAndrew CW, Donoghue DJ. (2007) Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis. Cell Cycle (Georgetown, Tex.). 6: 1188-93
Gastwirt RF, Slavin DA, McAndrew CW, et al. (2006) Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation. The Journal of Biological Chemistry. 281: 35425-35
Meyer AN, Gastwirt RF, Schlaepfer DD, et al. (2004) The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation. The Journal of Biological Chemistry. 279: 28450-7
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