David Gonzalez, Ph.D.

Affiliations: 
2011 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Biochemistry, Chemical Biology, Mass spectrometry; Harvesting genomic information for therapeutics
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Parents

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Pieter C. Dorrestein grad student 2011 UCSD
 (The use of mass spectrometry to characterize the metabolic output of bacterial pathogens.)
Jack E. Dixon post-doc UCSD School of Medicine
Victor Nizet post-doc 2011-2014 UCSD (Microtree)

Children

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Charlie Bayne grad student UCSD
Anaamika Campeau grad student UCSD
Dominic McGrosso grad student UCSD
Robert Mills grad student UCSD
Concepcion Sanchez grad student UCSD
Consuelo Sauceda grad student UCSD
Jacob Wozniak grad student UCSD
Carlos Gonzalez post-doc UCSD
John Lapek post-doc UCSD
Igor Wierzbicki post-doc UCSD
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Publications

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Buzun E, Hsu CY, Sejane K, et al. (2024) A bacterial sialidase mediates early-life colonization by a pioneering gut commensal. Cell Host & Microbe
Buzun E, Hsu CY, Sejane K, et al. (2023) A bacterial sialidase mediates early life colonization by a pioneering gut commensal. Biorxiv : the Preprint Server For Biology
Gu L, Zhu Y, Watari K, et al. (2023) Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metabolism
Patel A, McGrosso D, Hefner Y, et al. (2023) Proteome allocation is linked to transcriptional regulation through a modularized transcriptome. Biorxiv : the Preprint Server For Biology
Hayat O, Ullah N, Sirajuddin M, et al. (2022) A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using . Pathogens (Basel, Switzerland). 11
Sauceda C, Bayne C, Sudqi K, et al. (2022) Stool multi-omics for the study of host-microbe interactions in inflammatory bowel disease. Gut Microbes. 14: 2154092
Elsaid K, Merriman TR, Rossitto LA, et al. (2022) Amplification of inflammation by lubricin deficiency implicated in incident, erosive gout independent of hyperuricemia. Arthritis & Rheumatology (Hoboken, N.J.)
Lordén G, Wozniak JM, Doré K, et al. (2022) Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model. Nature Communications. 13: 7200
Pilo CA, Baffi TR, Kornev AP, et al. (2022) Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition. Science Signaling. 15: eabk1147
Gonzalez CG, Mills RH, Zhu Q, et al. (2022) Location-specific signatures of Crohn's disease at a multi-omics scale. Microbiome. 10: 133
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