Christopher B. Phelps, Ph.D.
Affiliations: | 2003 | University of California, San Diego, La Jolla, CA |
Area:
transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactionsGoogle:
"Christopher Phelps"Mean distance: 10.13 | S | N | B | C | P |
Parents
Sign in to add mentor| Gourisankar Ghosh | grad student | 2003 | UCSD | |
| (Interactions that regulate nuclear factor kappaB mediated transcription.) | ||||
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Publications
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| Tian X, Suarez D, Thomson D, et al. (2022) Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening. Journal of Medicinal Chemistry |
| Machutta CA, Kollmann CS, Lind KE, et al. (2018) Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening. Nature Communications. 9: 16227 |
| Lu X, Fan L, Phelps C, et al. (2017) Ruthenium Promoted On-DNA Ring-Closing Metathesis and Cross-Metathesis. Bioconjugate Chemistry |
| Phelps CB, Wang RR, Choo SS, et al. (2010) Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain. The Journal of Biological Chemistry. 285: 731-40 |
| Phelps CB, Huang RJ, Lishko PV, et al. (2008) Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels. Biochemistry. 47: 2476-84 |
| Phelps CB, Procko E, Lishko PV, et al. (2007) Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels. Channels (Austin, Tex.). 1: 148-51 |
| Lishko PV, Procko E, Jin X, et al. (2007) The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron. 54: 905-18 |
| Huang DB, Phelps CB, Fusco AJ, et al. (2005) Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB. Journal of Molecular Biology. 346: 147-60 |
| Phelps CB, Ghosh G. (2004) Discreet mutations from c-Rel to v-Rel alter kappaB DNA recognition, IkappaBalpha binding, and dimerization: implications for v-Rel oncogenicity. Oncogene. 23: 1229-38 |
| Huxford T, Mishler D, Phelps CB, et al. (2002) Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation. Journal of Molecular Biology. 324: 587-97 |