Jacky C. Ngo, Ph.D.

Affiliations: 
2006 University of California, San Diego, La Jolla, CA 
Area:
transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactions
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"Jacky Ngo"
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SNBCP

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Gourisankar Ghosh grad student 2006 UCSD
 (SR protein kinase 1: Conformation, substrate recognition and catalysis.)
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Publications

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Cheung MY, Ngo JC, Chen Z, et al. (2020) A Structure Model Explaining the Binding Between a Ubiquitous Unconventional G-protein (OsYchF1) and a Plant-Specific C2-Domain Protein (OsGAP1) from Rice. The Biochemical Journal
Chau DD, Yung KW, Chan WW, et al. (2019) Attenuation of amyloid-β generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802825RR
Liu M, Lo EC, Wang G, et al. (2017) Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening. Antiviral Research
Kromann-Hansen T, Oldenburg E, Yung KW, et al. (2016) A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior. The Journal of Biological Chemistry
Zhang Q, Tsoi H, Peng S, et al. (2016) A peptidylic inhibitor-based therapeutic approach that simultaneously suppresses RNA- and protein-mediated toxicities in polyglutamine diseases. Disease Models & Mechanisms
Chow WN, Ngo JC, Li W, et al. (2015) Phosphorylation of FE65 Serine-610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing. The Biochemical Journal
Liang N, Zeng C, Tao KP, et al. (2014) Primary structural features of SR-like protein acinusS govern the phosphorylation mechanism by SRPK2. The Biochemical Journal. 459: 181-91
Yuan C, Chen L, Meehan EJ, et al. (2011) Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. Bmc Structural Biology. 11: 30
Wong KK, Ngo JC, Liu S, et al. (2010) Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and kinetic analysis. Chemico-Biological Interactions. 187: 335-9
Huynh N, Ma CT, Giang N, et al. (2009) Allosteric interactions direct binding and phosphorylation of ASF/SF2 by SRPK1. Biochemistry. 48: 11432-40
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