Derek James Taylor, Ph.D.

2003 University of California, San Diego, La Jolla, CA 
 2009- Department of Pharmacology Case Western Reserve University, Cleveland Heights, OH, United States 
DNA maintenance and RNA maturation and biogenesis, bacterial and protozoan pathogenesis
"Derek Taylor"

Taylor received his BS degree from Fort Lewis College in Durango CO and his PhD from the University of California, San Diego. Dr. Taylor was an HHMI-sponsored postdoctoral fellow in the lab of Nobel Laureate Dr. Joachim Frank, where he learned cryo-electron microscopy (cryo-EM) and its application in structure determination of biological complexes. Dr. Taylor then spent a year working with Dr. Tom Cech (another Nobel Laureate) and his group where he began to investigate the structure and function of telomere complexes. Dr. Taylor began his independent position in 2009 when he joined the Department of Pharmacology at Case Western Reserve University. Dr. Taylor has been recognized with a Research Scholar Award from the American Cancer Society and a prestigious Director’s New Innovator Award from the NIH.
(Show less)

Mean distance: 9.33


Sign in to add mentor
Partho Ghosh grad student 2003 UCSD
 (Molecular and biophysical analysis of a conformational change in a nonenveloped RNA virus.)
John E. Johnson grad student 1999-2004 UCSD
 (Molecular and biophysical analysis of a conformational change in a nonenveloped RNA virus.)
Joachim Frank post-doc 2004-2008 HHMI
Thomas R. Cech post-doc 2008-2009 CU Boulder
BETA: Related publications


You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

des Georges A, Hashem Y, Unbehaun A, et al. (2014) Structure of the mammalian ribosomal pre-termination complex associated with eRF1.eRF3.GDPNP. Nucleic Acids Research. 42: 3409-18
Taylor D, Unbehaun A, Li W, et al. (2012) Cryo-EM structure of the mammalian eukaryotic release factor eRF1-eRF3-associated termination complex. Proceedings of the National Academy of Sciences of the United States of America. 109: 18413-8
Taylor DJ, Podell ER, Taatjes DJ, et al. (2011) Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA. Journal of Molecular Biology. 410: 10-7
Speir JA, Taylor DJ, Natarajan P, et al. (2010) Evolution in action: N and C termini of subunits in related T = 4 viruses exchange roles as molecular switches. Structure (London, England : 1993). 18: 700-9
Taylor DJ, Devkota B, Huang AD, et al. (2009) Comprehensive molecular structure of the eukaryotic ribosome. Structure (London, England : 1993). 17: 1591-604
Shi Y, Di Giammartino DC, Taylor D, et al. (2009) Molecular architecture of the human pre-mRNA 3' processing complex. Molecular Cell. 33: 365-76
Grassucci RA, Taylor D, Frank J. (2008) Visualization of macromolecular complexes using cryo-electron microscopy with FEI Tecnai transmission electron microscopes. Nature Protocols. 3: 330-9
Grassucci RA, Taylor DJ, Frank J. (2007) Preparation of macromolecular complexes for cryo-electron microscopy. Nature Protocols. 2: 3239-46
Frank J, Gao H, Sengupta J, et al. (2007) The process of mRNA-tRNA translocation. Proceedings of the National Academy of Sciences of the United States of America. 104: 19671-8
Taylor DJ, Nilsson J, Merrill AR, et al. (2007) Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation. The Embo Journal. 26: 2421-31
See more...