Zhiru Yang, Ph.D.

Affiliations: 
2003 Columbia University, New York, NY 
Area:
Structural Molecular Biology
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"Zhiru Yang"
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Liang Tong grad student 2003 Columbia
 (Structural and biochemical studies on malic enzymes.)
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Publications

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Tao X, Yang Z, Tong L. (2003) Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure (London, England : 1993). 11: 1141-50
Zhang H, Yang Z, Shen Y, et al. (2003) Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science (New York, N.Y.). 299: 2064-7
Yang Z, Savchenko A, Yakunin A, et al. (2003) Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643. The Journal of Biological Chemistry. 278: 8804-8
Yang Z, Lanks CW, Tong L. (2002) Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate. Structure (London, England : 1993). 10: 951-60
Yang Z, Zhang H, Hung HC, et al. (2002) Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme. Protein Science : a Publication of the Protein Society. 11: 332-41
Rishavy MA, Yang Z, Tong L, et al. (2001) Determination of the mechanism of human malic enzyme with natural and alternate dinucleotides by isotope effects. Archives of Biochemistry and Biophysics. 396: 43-8
Hung HC, Chang GG, Yang Z, et al. (2000) Slow binding of metal ions to pigeon liver malic enzyme: a general case. Biochemistry. 39: 14095-102
Yang Z, Batra R, Floyd DL, et al. (2000) Potent and competitive inhibition of malic enzymes by lanthanide ions. Biochemical and Biophysical Research Communications. 274: 440-4
Yang Z, Floyd DL, Loeber G, et al. (2000) Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nature Structural Biology. 7: 251-7
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