Linda P. Yu, Ph.D.

Affiliations: 
2012 Biological Sciences Columbia University, New York, NY 
Area:
Structural Molecular Biology
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"Linda Yu"
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Liang Tong grad student 2012 Columbia
 (Structural and functional studies of Staphylococcus aureus pyruvate carboxylase.)
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Publications

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Lasso G, Yu LP, Gil D, et al. (2014) Functional conformations for pyruvate carboxylase during catalysis explored by cryoelectron microscopy. Structure (London, England : 1993). 22: 911-22
Yu LP, Chou CY, Choi PH, et al. (2013) Characterizing the importance of the biotin carboxylase domain dimer for Staphylococcus aureus pyruvate carboxylase catalysis. Biochemistry. 52: 488-96
Yu LP, Kim YS, Tong L. (2010) Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden. Proceedings of the National Academy of Sciences of the United States of America. 107: 22072-7
Lasso G, Yu LP, Gil D, et al. (2010) Cryo-EM analysis reveals new insights into the mechanism of action of pyruvate carboxylase. Structure (London, England : 1993). 18: 1300-10
Yu LP, Xiang S, Lasso G, et al. (2009) A symmetrical tetramer for S. aureus pyruvate carboxylase in complex with coenzyme A. Structure (London, England : 1993). 17: 823-32
Chou CY, Yu LP, Tong L. (2009) Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. The Journal of Biological Chemistry. 284: 11690-7
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