Brian R. Simler, Ph.D.

Affiliations: 
2004 Pennsylvania State University, State College, PA, United States 
Area:
Protein Folding
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"Brian Simler"
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C. Robert Matthews grad student 2004 Penn State
 (Characterization of the folding energy landscapes of two multimeric proteins: Trp repressor from Escherichia coli and carbonic anhydrase from Methanosarcina thermophila.)
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Publications

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Simler BR, Levy Y, Onuchic JN, et al. (2006) The folding energy landscape of the dimerization domain of Escherichia coli Trp repressor: a joint experimental and theoretical investigation. Journal of Molecular Biology. 363: 262-78
Simler BR, Doyle BL, Matthews CR. (2004) Zinc binding drives the folding and association of the homo-trimeric gamma-carbonic anhydrase from Methanosarcina thermophila. Protein Engineering, Design & Selection : Peds. 17: 285-91
Gloss LM, Simler BR, Matthews CR. (2001) Rough energy landscapes in protein folding: dimeric E. coli Trp repressor folds through three parallel channels. Journal of Molecular Biology. 312: 1121-34
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