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Brandon E. Aubol, Ph.D.

Affiliations: 
2005 University of California, San Diego, La Jolla, CA 
Area:
protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies
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"Brandon Aubol"
Mean distance: 9.81
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Patricia A. Jennings grad student 2005 UCSD
 (Mechanistic characterization of SR protein kinases using their physiological protein substrates.)

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Publications

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Aubol BE, Adams JA. (2022) SRPK1 regulates RNA binding in a pre-spliceosomal complex using a catalytic bypass mechanism. The Febs Journal
Aubol BE, Wozniak JM, Fattet L, et al. (2021) CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly. Proceedings of the National Academy of Sciences of the United States of America. 118
Fattet L, Jung HY, Matsumoto MW, et al. (2020) Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex. Developmental Cell
Aubol BE, Fattet L, Adams JA. (2020) A Conserved Sequence Motif Bridges Two Protein Kinases For Enhanced Phosphorylation and Nuclear Function of A Splicing Factor. The Febs Journal
Gou LT, Lim DH, Ma W, et al. (2020) Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation. Cell
George A, Aubol BE, Fattet L, et al. (2019) Disordered protein interactions for an ordered cellular transition: Cdc-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate. The Journal of Biological Chemistry
Aubol BE, Serrano P, Fattet L, et al. (2018) Molecular Interactions Connecting the Function of the Serine-Arginine-rich protein SRSF1 to Protein Phosphatase 1. The Journal of Biological Chemistry
Aubol BE, Keshwani MM, Fattet L, et al. (2018) Mobilization of A Splicing Factor Through A Nuclear Kinase-Kinase Complex. The Biochemical Journal
Aubol BE, Hailey KL, Fattet L, et al. (2017) Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform. Journal of Molecular Biology
Aubol BE, Wu G, Keshwani MM, et al. (2016) Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Molecular Cell
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