Carrie A. Hughes, Ph.D.

Affiliations: 
2003 University of California, San Diego, La Jolla, CA 
Area:
Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics
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"Carrie Hughes"
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Elizabeth A. Komives grad student 2003 UCSD
 (Protein -protein interactions and dynamics probed by hydrogen /deuterium exchange.)
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Publications

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Huxford T, Mishler D, Phelps CB, et al. (2002) Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation. Journal of Molecular Biology. 324: 587-97
Anand GS, Hughes CA, Jones JM, et al. (2002) Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A. Journal of Molecular Biology. 323: 377-86
Baerga-Ortiz A, Hughes CA, Mandell JG, et al. (2002) Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein. Protein Science : a Publication of the Protein Society. 11: 1300-8
Komives EA, Baerga-Ortiz A, Mandell JG, et al. (2002) Biophysics of protein-protein interfaces using biacore, NMR and amide exchange Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 119-120
Hughes CA, Mandell JG, Anand GS, et al. (2001) Phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of methylesterase CheB. Journal of Molecular Biology. 307: 967-76
Schengrund CL, DasGupta BR, Hughes CA, et al. (1996) Ganglioside-induced adherence of botulinum and tetanus neurotoxins to adducin. Journal of Neurochemistry. 66: 2556-61
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