Scott B. Hansen, Ph.D.

Affiliations: 
Scripps Institute, Florida  
Area:
Biochemistry
Website:
https://www.scripps.edu/faculty/hansen/
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Palmer W. Taylor grad student 2005 UCSD
 (Ligand specificity and conformational states of the acetylcholine binding protein, a nicotinic receptor surrogate.)
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Publications

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Pavel MA, Petersen EN, Wang H, et al. (2020) Studies on the mechanism of general anesthesia. Proceedings of the National Academy of Sciences of the United States of America
Petersen EN, Pavel MA, Wang H, et al. (2019) Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels. Biochimica Et Biophysica Acta. Biomembranes. 183091
Robinson CV, Rohacs T, Hansen SB. (2019) Tools for Understanding Nanoscale Lipid Regulation of Ion Channels. Trends in Biochemical Sciences
Chung HW, Nicholas Petersen E, Cabanos C, et al. (2018) A Molecular Target for an Alcohol Chain Length Cutoff. Journal of Molecular Biology
Cabanos C, Wang M, Han X, et al. (2017) A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Reports. 20: 1287-1294
Hansen SB. (2015) Lipid agonism: The PIP2 paradigm of ligand-gated ion channels. Biochimica Et Biophysica Acta. 1851: 620-628
Hansen SB, Tao X, MacKinnon R. (2011) Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2. Nature. 477: 495-8
Sine SM, Wang HL, Hansen S, et al. (2010) On the origin of ion selectivity in the Cys-loop receptor family. Journal of Molecular Neuroscience : Mn. 40: 70-6
Hansen SB, Wang HL, Taylor P, et al. (2008) An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance. The Journal of Biological Chemistry. 283: 36066-70
Taylor P, Talley TT, Radic' Z, et al. (2007) Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochemical Pharmacology. 74: 1164-71
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